HMG-CoA reductase inhibitors (statins) are a widely used class of drug, and like all
medications, have potential for adverse effects (AEs). Here we review the statin AE literature …

The elderly differ from younger people in the relation of cholesterol to heart disease and
mortality. Clinical trial evidence supports epidemiological findings in showing that high …

There is an increasing burden of occlusive cardiovascular disease (CVD) in developed, as
well as in developing, countries. In fact, the WHO has projected that CVD will become the …

Peripheral arterial disease (PAD) is a common condition associated with an increased risk
of coronary heart disease, myocardial infarction and stroke. It follows that PAD merits …

Introduction Vascular intimal hyperplasia is associated with increased mortality and
morbidity. The authors investigated the effects of atorvastatin on vascular intimal …

Purpose Our previous studies have confirmed that aspirin combined with Lipitor inhibited the
development of prostate cancer (PCa), but the mechanisms need to be comprehensively …

Fabry disease is an X‐linked glycosphingolipid storage disorder resulting from deficiency of
α‐galactosidase A. Storage of globotriaosylceramide ultimately results in multiorgan …

Cardiovascular disease (CVD) is and will remain the leading avoidable cause of premature
deaths in the USA and is rapidly becoming so worldwide. The totality of available evidence …

Objective: The clinical literature suggests that atorvastatin therapy achieves a reduction in
major cardiovascular events within the first year of therapy. Aside from obvious clinical …

The Ph-negative chronic myeloproliferative disorders (CMPDs) polycythaemia vera,
essential thrombocytosis and idiopathic myelofibrosis are acquired stem cell disorders …