Recently published work and emerging research efforts have suggested that the olfactory
system is intimately linked with the endocrine systems that regulate or modify energy …

Type 2 diabetes mellitus (T2DM) is common and increasing in prevalence worldwide, with
devastating public health consequences. While peripheral insulin resistance is a key feature …

Asprosin is a fasting-induced hormone that promotes glucose production in the liver and
stimulates appetite in the hypothalamus by activating the cAMP signaling pathway via an …

Obesity is a risk factor for SARS-CoV-2 infected patients to develop respiratory failure. Leptin
produced in visceral fat might play a role in the deterioration to mechanical ventilation. A …

CNS axons differ in diameter (d) by nearly 100-fold (∼ 0.1–10 μm); therefore, they differ in
cross-sectional area (d 2) and volume by nearly 10,000-fold. If, as found for optic nerve …

Olfactory inputs help coordinate food appreciation and selection, but their role in systemic
physiology and energy balance is poorly understood. Here we demonstrate that mice upon …

The sense of smell is found widely in the animal kingdom. Human and animal studies show
that odor perception is modulated by experience and/or physiological state (such as …

Background Adaptive behavioral prioritization requires flexible outputs from fixed neural
circuits. In C. elegans, the prioritization of feeding versus mate searching depends on …

Taste detection and hunger state dynamically regulate the decision to initiate feeding. To
study how context-appropriate feeding decisions are generated, we combined synaptic …

Mechanosensitive cells are essential for organisms to sense the external and internal
environments, and a variety of molecules have been implicated as mechanical sensors …