With aging, the incidence of age-related diseases increases. Hence, age-related diseases
are inevitable. However, the mechanisms by which aging leads to the onset and progression …

Ischemic stroke, a primary cause of disability and the second leading cause of mortality, has
emerged as an urgent public health issue. Growing evidence suggests that the Cyclic GMP …

Immunotherapy occupies an increasingly important place in the field of tumor treatment. The
cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, which is …

The cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) synthase-
stimulator of interferon genes (cGAS-STING) signaling pathway, an important component of …

Background Atherosclerosis (AS) is the most prevalent cardiovascular disease, with an
exceptionally high burden. High-fat diet (HFD) is a popular diet behavior, whereas low-dose …

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling
pathway is one of the fundamental mechanisms of the body's defense, which responds to …

Background Patients with systemic sclerosis (SSc) are known to have higher incidence of
atherosclerosis (AS). Mitochondrial injuries in SSc can cause endothelial dysfunction …