Host immune responses to salivary components-a critical facet of tick-host interactions
Tick sialome is comprised of a rich cocktail of bioactive molecules that function as a tool to
disarm host immunity, assist blood-feeding, and play a vibrant role in pathogen …
disarm host immunity, assist blood-feeding, and play a vibrant role in pathogen …
Serpins in tick physiology and tick-host interaction
MN Abbas, A Chlastáková, MA Jmel… - Frontiers in Cellular …, 2022 - frontiersin.org
Tick saliva has been extensively studied in the context of tick-host interactions because it is
involved in host homeostasis modulation and microbial pathogen transmission to the host …
involved in host homeostasis modulation and microbial pathogen transmission to the host …
Understanding tick biology and its implications in anti-tick and transmission blocking vaccines against tick-borne pathogens
B Bhowmick, Q Han - Frontiers in Veterinary Science, 2020 - frontiersin.org
Ticks are obligate blood-feeding ectoparasites that transmit a wide variety of pathogens to
animals and humans in many parts of the world. Currently, tick control methods primarily rely …
animals and humans in many parts of the world. Currently, tick control methods primarily rely …
Tick salivary compounds for targeted immunomodulatory therapy
H Aounallah, C Bensaoud, Y M'ghirbi, F Faria… - Frontiers in …, 2020 - frontiersin.org
Immunodeficiency disorders and autoimmune diseases are common, but a lack of effective
targeted drugs and the side-effects of existing drugs have stimulated interest in finding …
targeted drugs and the side-effects of existing drugs have stimulated interest in finding …
Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules
A Chlastáková, B Kaščáková, J Kotál… - Frontiers in …, 2023 - frontiersin.org
Serpins are widely distributed and functionally diverse inhibitors of serine proteases. Ticks
secrete serpins with anti-coagulation, anti-inflammatory, and immunomodulatory activities …
secrete serpins with anti-coagulation, anti-inflammatory, and immunomodulatory activities …
Allergic reactions and immunity in response to tick salivary biogenic substances and red meat consumption in the zebrafish model
M Contreras, I Pacheco, P Alberdi… - Frontiers in Cellular …, 2020 - frontiersin.org
Ticks are arthropod ectoparasite vectors of pathogens and the cause of allergic reactions
affecting human health worldwide. In humans, tick bites can induce high levels of …
affecting human health worldwide. In humans, tick bites can induce high levels of …
Iripin-3, a New Salivary Protein Isolated From Ixodes ricinus Ticks, Displays Immunomodulatory and Anti-Hemostatic Properties In Vitro
A Chlastáková, J Kotál, Z Beránková… - Frontiers in …, 2021 - frontiersin.org
Tick saliva is a rich source of pharmacologically and immunologically active molecules.
These salivary components are indispensable for successful blood feeding on vertebrate …
These salivary components are indispensable for successful blood feeding on vertebrate …
Structure and function of a family of tick-derived complement inhibitors targeting properdin
Activation of the serum-resident complement system begins a cascade that leads to
activation of membrane-resident complement receptors on immune cells, thus coordinating …
activation of membrane-resident complement receptors on immune cells, thus coordinating …
Resistance to ticks and the path to anti-tick and transmission blocking vaccines
JG van Oosterwijk, SK Wikel - Vaccines, 2021 - mdpi.com
The medical and veterinary public health importance of ticks and tick-borne pathogens is
increasing due to the expansion of the geographic ranges of both ticks and pathogens …
increasing due to the expansion of the geographic ranges of both ticks and pathogens …
RNA-seq analysis and gene expression dynamics in the salivary glands of the argasid tick Ornithodoros erraticus along the trophogonic cycle
R Pérez-Sánchez, Á Carnero-Morán, B Soriano… - Parasites & …, 2021 - Springer
Abstract Background The argasid tick Ornithodoros erraticus is the main vector of tick-borne
human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin …
human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin …