Keratoconus is a bilateral and asymmetric disease which results in progressive thinning and
steeping of the cornea leading to irregular astigmatism and decreased visual acuity …

Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of …

Purpose Single cell (sc) analyses of key embryonic, fetal and adult stages were performed to
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell …

Purpose To optimize artificial intelligence (AI) algorithms to integrate Scheimpflug-based
corneal tomography and biomechanics to enhance ectasia detection. Design Multicenter …

Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

The extracellular matrix (ECM) is a highly dynamic and heterogeneous structure that plays
multiple roles in living organisms. Its integrity and homeostasis are crucial for normal tissue …

Keratoconus is the most common corneal ectatic disorder. It is characterized by progressive
corneal thinning with resultant irregular astigmatism and myopia. Its prevalence has been …

Purpose: To identify and assess the quality of questionnaires used to measure quality of life
in keratoconus and guide selection of the most appropriate questionnaire for evaluating the …

Corneal imaging is essential for diagnosing and management of a wide variety of ocular
diseases. Corneal topography is used to characterize the shape of the cornea, specifically …

Keratoconus is characterised by reduced rigidity of the cornea with distortion and focal
thinning that causes blurred vision, however, the pathogenetic mechanisms are unknown. It …