Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren's syndrome

MJ Barrera, S Aguilera, I Castro, P Carvajal, D Jara… - Autoimmunity …, 2021 - Elsevier
Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …

[HTML][HTML] Histone modifications and non-coding RNAs: mutual epigenetic regulation and role in pathogenesis

IV Bure, MV Nemtsova, EB Kuznetsova - International Journal of …, 2022 - mdpi.com
In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …

Multiomics and machine learning accurately predict clinical response to adalimumab and etanercept therapy in patients with rheumatoid arthritis

W Tao, AN Concepcion, M Vianen… - Arthritis & …, 2021 - Wiley Online Library
Objective To predict response to anti–tumor necrosis factor (anti‐TNF) prior to treatment in
patients with rheumatoid arthritis (RA), and to comprehensively understand the mechanism …

[HTML][HTML] COVID-19 and rheumatoid arthritis crosstalk: emerging association, therapeutic options and challenges

S Dewanjee, R Kandimalla, RS Kalra, C Valupadas… - Cells, 2021 - mdpi.com
Hyperactivation of immune responses resulting in excessive release of pro-inflammatory
mediators in alveoli/lung structures is the principal pathological feature of coronavirus …

[HTML][HTML] Epigenetic changes in the pathogenesis of rheumatoid arthritis

MV Nemtsova, DV Zaletaev, IV Bure… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Medicinal plants used against various inflammatory biomarkers for the management of rheumatoid arthritis

S Singh, TG Singh, K Mahajan… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives Rheumatoid arthritis is a chronic autoimmune disease manifested clinically by
polyarthralgia associated with joint dysfunction triggering the antibodies targeting against …

[HTML][HTML] Advances in anti-inflammatory medicinal plants and phytochemicals in the management of arthritis: A comprehensive review

Y Gandhi, R Kumar, J Grewal, H Rawat… - Food chemistry …, 2022 - Elsevier
Rheumatoid arthritis (RA) is considered to be an inflammatory disorder whereas OA is not
an overtly inflammatory disorder as RA but certain inflammatory cytokines and periodic …

[HTML][HTML] Recent insights into the role of macrophages in acute gout

L Liu, L Zhu, M Liu, L Zhao, Y Yu, Y Xue… - Frontiers in …, 2022 - frontiersin.org
Gout is a common type of inflammatory arthritis characterized by the presence of
monosodium urate crystals (MSU) in the joints. Macrophages are believed to be involved in …

Rheumatoid arthritis and inflammatory bowel disease: A bidirectional two-sample Mendelian randomization study

C Meisinger, D Freuer - Seminars in arthritis and rheumatism, 2022 - Elsevier
Objectives An association between arthritis and inflammatory bowel disease (IBD) was
found in observational studies. However, neither the direction nor the cause-effect chain is …

[HTML][HTML] Clinical effect and biological mechanism of exercise for rheumatoid arthritis: A mini review

Z Li, XQ Wang - Frontiers in Immunology, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is a common systematic, chronic inflammatory, autoimmune, and
polyarticular disease, causing a range of clinical manifestations, including joint swelling …