Neurodegenerative diseases resulting from the progressive loss of structure and/or function
of neurons contribute to different paralysis degrees and loss of cognition and sensation. The …

Progressive supranuclear palsy (PSP) is an atypical parkinsonism with prominent 4R-tau
neuropathology, and the classical clinical phenotype is characterized by vertical …

Alzheimer's disease (AD), Parkinson's disease (PD), frontotemporal dementia (FTD),
amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and prion diseases have a …

Abstract Purpose of Review In this review, we highlight recent advances in the human
genetics of frontotemporal dementia (FTD). In addition to providing a broad survey of genes …

C9orf72 repeat expansions is a major cause of familial frontotemporal dementia (FTD) and
amyotrophic lateral sclerosis (ALS) worldwide. Sizes of< 20 hexanucleotide repeats are …

With the development of the sequencing technique, more than 40 repeat expansion
diseases (REDs) have been identified during the past two decades. Moreover, the clinical …

Background Frontotemporal lobar degeneration with tauopathy caused by MAPT
(microtubule‐associated protein tau) mutations is a highly heterogenous disorder. The …

Background Behavioral variant frontotemporal dementia (bvFTD) is a clinically
heterogeneous syndrome with high heredity. However, the frequencies of mutations …

Frontotemporal dementia (FTD) presents with a wide variability in clinical syndromes,
genetic etiologies, and underlying pathologies. Despite the discovery of pathogenic variants …

Background: Microtubule-associated protein tau (MAPT) mutations are one of the main
causes of genetic Frontotemporal dementia (FTD) and are characterised by high clinical …