Predominant ligament-centric soft-tissue involvement differentiates axial psoriatic arthritis from ankylosing spondylitis

D McGonagle, P David, T Macleod… - Nature Reviews …, 2023 - nature.com
Since the original description of spondyloarthritis 50 years ago, results have demonstrated
similarities and differences between ankylosing spondylitis (AS) and axial psoriatic arthritis …

[HTML][HTML] The Role of Early Treatment in the Management of Axial Spondyloarthritis: Challenges and Opportunities

D Mauro, G Forte, D Poddubnyy, F Ciccia - Rheumatology and Therapy, 2024 - Springer
Axial spondyloarthritis (axSpA) is a chronic, inflammatory rheumatic disease that primarily
affects the axial skeleton, often inflicting severe pain, diminished mobility, and a …

IL-23 induces CLEC5A+ IL-17A+ neutrophils and elicit skin inflammation associated with psoriatic arthritis

H Furuya, CT Nguyen, T Chan, AI Marusina… - Journal of …, 2024 - Elsevier
Abstract IL-23-activation of IL-17 producing T cells is involved in many rheumatic diseases.
Herein, we investigate the role of IL-23 in the activation of myeloid cell subsets that …

[HTML][HTML] The failure of biological treatment in axial spondyloarthritis is linked to the factors related to increased intestinal permeability and dysbiosis: prospective …

M Chmielińska, A Felis-Giemza, M Olesińska… - Rheumatology …, 2024 - Springer
Background A significant number of patients with axial spondyloarthritis (axSpA) do not
respond to biological therapy. Therefore, we decided to investigate the specificity of this …

[HTML][HTML] Is sarcopenia a real concern in ankylosing spondylitis? A systematic literature review

C Ceolin, MV Papa, L Scagnellato, A Doria… - European Geriatric …, 2024 - Springer
Purpose Sarcopenia is a condition defined as loss of muscle mass and strength, associated
with poor functional performance and disability. Sarcopenia can be exacerbated or …

Short-term effectiveness of guselkumab in psoriatic arthritis patients and axial involvement: results from a real-life multicentre cohort

P Ruscitti, I Pantano, G Cataldi, M Gentile… - …, 2024 - academic.oup.com
Objective To evaluate the short-term effectiveness of guselkumab in patients with psoriatic
arthritis (PsA) and suggestive features of axial involvement in a prospective 'real …

[HTML][HTML] Beyond the horizon: Innovations and future directions in axial-spondyloarthritis

V Venerito, S Del Vescovo, G Lopalco… - Archives of …, 2023 - ncbi.nlm.nih.gov
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease of the spine and sacroiliac
joints. This review discusses recent advances across multiple scientific fields that promise to …

Effects of disease-modifying anti-rheumatic drugs on sacroiliac MRI score in axial spondyloarthritis: a systematic review and meta-analysis

A Hansmaennel, O Fakih, A Gerazime, C Prati… - Clinical …, 2024 - Springer
Introduction Sacroiliac bone marrow edema is an important factor in the diagnosis and
management of axial spondyloarthritis (axSpA). The aim of this meta-analysis is to assess …

Exploring radiographic patterns of the cervical spine, including zygapophyseal joints, in axial spondyloarthritis

L Berbel-Arcobé, D Benavent, X Michelena… - RMD open, 2024 - rmdopen.bmj.com
Introduction The assessment of the cervical spine (CS) in axial spondyloarthritis (axSpA)
and its radiographic characteristics, including the zygapophyseal joints (ZJ), may be helpful …