The alveolar epithelial glycocalyx is a dense anionic layer of glycosaminoglycans (GAGs)
and proteoglycans that lines the apical surface of the alveolar epithelium. In contrast to the …

Hermansky-Pudlak Syndrome (HPS) is a rare, genetic, multisystem disorder characterized
by oculocutaneous albinism (OCA), bleeding diathesis, immunodeficiency, granulomatous …

Lipids are major actors and regulators of physiological processes within the lung. Initial
research has described their critical role in tissue homeostasis and in orchestrating cellular …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, and highly fatal
disease. It is characterized by the increased activation of both fibroblast and myofibroblast …

Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease of unknown etiology.
Different types of cells are involved in fibrogenesis, which is persistently physical and …

The main physiological function of the lung is gas exchange, mediated at the interface
between the alveoli and the pulmonary microcapillary network and facilitated by conducting …

Extracellular vesicles (EVs) are anuclear particles composed of lipid bilayers that contain
nucleic acids, proteins, lipids, and organelles. EVs act as an important mediator of cell-to …

CYP2J2, a member of the Cytochrome P450 family of enzymes, is the most abundant
epoxygenase in the heart and has multifunctional properties including bioactivation of …

This study investigated immune cell characteristics in chronic hypersensitivity pneumonitis
(HP), focusing on CD39-expressing cells' impact on inflammation and tissue remodelling …

The heterogeneity of fibroblasts in the murine and human lung during homeostasis and
disease is increasingly recognized. It remains unclear if the different phenotypes identified to …