Syndecan-1 amplifies ovalbumin-induced airway remodeling by strengthening TGFβ1/Smad3 action

D Zhang, X Qiao, WJ Cui, J Zhang, Y Pan… - Frontiers in …, 2021 - frontiersin.org
Syndecan-1 (SDC-1) is a transmembrane proteoglycan of heparin sulfate that can regulate
various cell signal transduction pathways in the airway epithelial cells and fibroblasts …

Fibroblasts-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis

O Burgy, CH Mayr, BB Llobell, A Sengupta… - bioRxiv, 2022 - biorxiv.org
Idiopathic pulmonary fibrosis (IPF) is a lethal and chronic lung disease characterized by
aberrant intercellular communication, increased extracellular matrix (ECM) deposition, and …

[HTML][HTML] Deciphering the Role of Proteoglycans and Glycosaminoglycans in Health and Disease: The role of the alveolar epithelial glycocalyx in acute respiratory …

AN Rizzo, EP Schmidt - American Journal of Physiology-Cell …, 2023 - ncbi.nlm.nih.gov
The alveolar epithelial glycocalyx is a dense anionic layer of glycosaminoglycans (GAGs)
and proteoglycans that lines the apical surface of the alveolar epithelium. In contrast to the …

Endotheliopathy of trauma in children: The association of syndecan-1 with injury and poor outcomes

KM Morgan, E Abou-Khalil, BA Gaines… - Journal of trauma and …, 2023 - journals.lww.com
Background The contribution of the endothelium to trauma-induced coagulopathy has not
been thoroughly investigated in injured children. Methods This is a prospective cohort study …

[HTML][HTML] Breast-conserving surgery and sentinel lymph node biopsy for breast cancer and their correlation with the expression of polyligand proteoglycan-1

FM Li, DY Xu, Q Xu, Y Yuan - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
BACKGROUND Breast cancer is a malignant tumor with an unclear etiology and is the most
common malignant tumor in women. Surgery is the main clinical treatment for breast cancer …

Sindecan-1 and cardiovascular diseases

AM Alieva, TV Pinchuk, MA Batov, KV Voronkova… - Therapy, 2021 - journals.eco-vector.com
Today, the search and study of new biomarkers that can help the diagnosis of
cardiovascular diseases, serve as a tool for assessing the effectiveness of therapy, be a …

Синдекан-1 и сердечно-сосудистые заболевания

АМ Алиева, ТВ Пинчук, МА Батов, КВ ВОРОНКОВА… - Терапия, 2021 - elibrary.ru
На сегодняшний день остается актуальным поиск и изучение новых биомаркеров,
способных помогать в диагностике сердечно-сосудистых заболеваний, служить …

Hermansky-Pudlak Syndrome and Lung Disease: Pathogenesis and

P Velázquez-Díaz, E Nakajima… - Inflammatory …, 2022 - books.google.com
Hermansky-Pudlak Syndrome (HPS) is a rare, genetic, multisystem disorder characterized
by oculocutaneous albinism (OCA), bleeding diathesis, immunodeficiency, granulomatous …

The Immune Regulation of Idiopathic Pulmonary Fibrosis

T Miles - 2022 - research-repository.uwa.edu.au
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease characterised by
the excessive accumulation of scar tissue within the lung. At present, the cause of IPF is …

[HTML][HTML] Genetic signatures of acute asthma exacerbation related with ineffective response to corticosteroid

MG Kang, HS Lee, KG Tantisira… - Allergy, Asthma & …, 2020 - ncbi.nlm.nih.gov
Purpose Acute exacerbation (AE) is an important domain of asthma management and may
be related with ineffective response to corticosteroid. This study aimed to find mechanisms of …