▪ Abstract Multiple sclerosis (MS) develops in young adults with a complex predisposing
genetic trait and probably requires an inciting environmental insult such as a viral infection …

CNS inflammation is a major driver of MS pathology. Differential immune responses,
including the adaptive and the innate immune system, are observed at various stages of MS …

Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of
demyelination and axonal lesion mediated by CD4+ T cells with a proinflammatory Th1 and …

The Committee of the European Concerted Action for Multiple Sclerosis (Charcot
Foundation) organised five workshops to discuss CSF analytical standards in the diagnosis …

There is much evidence to implicate B cells, plasma cells, and their products in the
pathogenesis of MS. Despite unequivocal evidence that the animal model for MS, EAE, is …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system white
matter. The association of the disease with MHC genes, the inflammatory white matter …

Single-cell RT-PCR was used to sample CD19+ B cell repertoires in cerebrospinal fluid
(CSF) of patients with multiple sclerosis (MS) or viral meningitis. Analysis of amplified Ab H …

Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there
have been ever-increasing advances in the analyses of proteins, by electrophoresis in …

Multiple Sclerosis (MS) is an inflammatory disease of the Central Nervous System with
multifocal areas of demyelination. Although its etiology and pathogenesis remain …

Background: The authors have recently described that intrathecal IgM synthesis (ITMS)
correlates with a higher disability in patients with clinically definite MS (CDMS). Objective: To …