[HTML][HTML] Impact of supplementation and nutritional interventions on pathogenic processes of mood disorders: A review of the evidence

CT Hoepner, RS McIntyre, GI Papakostas - Nutrients, 2021 - mdpi.com
This narrative review was conducted using searches of the PubMed/Medline and Google
Scholar databases from inception to November 2019. Clinical trials and relevant articles …

Alpha-lipoic acid in the treatment of psychiatric and neurological disorders: a systematic review

CNS de Sousa, CMG da Silva Leite… - Metabolic brain …, 2019 - Springer
Despite the existence of many preclinical studies, scientific evidence is lacking on the
clinical use of alpha-lipoic acid (ALA) for central nervous system disorders. Therefore, we …

Involvement of oxidative pathways and BDNF in the antidepressant effect of carvedilol in a depression model induced by chronic unpredictable stress

CNS de Sousa, IS Medeiros, GS Vasconcelos… - …, 2022 - Springer
Rationale Depression is a severe psychiatric disorder with oxidative imbalance and
neurotrophic deficits as underlying mechanisms. Objectives Based on the antioxidant effects …

Evidence for protective effect of lipoic acid and desvenlafaxine on oxidative stress in a model depression in mice

MCC Silva, CNS de Sousa, PXL Gomes… - Progress in Neuro …, 2016 - Elsevier
Oxidative stress is implicated in the neurobiology of depression. Here we investigated
oxidative alterations in brain areas of animals submitted to the model of depression induced …

Reversal of corticosterone-induced BDNF alterations by the natural antioxidant alpha-lipoic acid alone and combined with desvenlafaxine: emphasis on the …

CNS de Sousa, LN Meneses, GS Vasconcelos… - Psychiatry …, 2015 - Elsevier
Brain derived neurotrophic factor (BDNF) is linked to the pathophysiology of depression. We
hypothesized that BDNF is one of the neurobiological pathways related to the augmentation …

Riparin II ameliorates corticosterone-induced depressive-like behavior in mice: Role of antioxidant and neurotrophic mechanisms

IS Lopes, ICM Oliveira, VCC Capibaribe… - Neurochemistry …, 2018 - Elsevier
Abstract Riparin II (RIP II) is an alkamide isolated from Aniba riparia that has presented
antidepressant and anxiolytic effects in acute stress behavioral models. This study aimed to …

Thymol reverses depression-like behaviour and upregulates hippocampal BDNF levels in chronic corticosterone-induced depression model in female mice

VCC Capibaribe… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Based on this, the central therapeutic effects of thymol were verified in the
neurotrophic pathway. Methods Female swiss mice were divided into four groups: control …

Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice

R de Castro Chaves, ASV Mallmann, NF Oliveira… - Pharmacology …, 2019 - Elsevier
Mental disorders have a multifactorial etiology and stress presents as one of the causal
factors. In depression, it is suggested that high cortisol concentration contributes directly to …

Behavioral and Neurochemical Effects of Alpha‐Lipoic Acid in the Model of Parkinson's Disease Induced by Unilateral Stereotaxic Injection of 6‐Ohda in Rat

DP de Araújo, CNS De Sousa… - Evidence‐Based …, 2013 - Wiley Online Library
This study aimed to investigate behavioral and neurochemical effects of α‐lipoic acid (100
mg/kg or 200 mg/kg) alone or associated with L‐DOPA using an animal model of …

Subchronic administration of riparin III induces antidepressive‐like effects and increases BDNF levels in the mouse hippocampus

AS Vasconcelos, ICM Oliveira… - Fundamental & …, 2015 - Wiley Online Library
Abstract Riparin III (Rip III) is an alcamide isolated from A niba riparia that has presented
effects of antidepressant and anxiolytic activities in acute stress behavioral models. The …