An update to biomechanical and biochemical principles of retinal injury in child abuse
K Shahraki, DW Suh - Children, 2024 - mdpi.com
Abusive head trauma (AHT) is an extreme form of physical child abuse, a subset of which is
shaken baby syndrome (SBS). While traumatic injury in children is most readily observed as …
shaken baby syndrome (SBS). While traumatic injury in children is most readily observed as …
MicroRNA miR-181d-5p regulates the MAPK signaling pathway by targeting mitogen-activated protein kinase 8 (MAPK8) to improve lupus nephritis
F Chai, H Peng, L Qin, C Liu, Y Zeng, R Wang, G Xu… - Gene, 2024 - Elsevier
Background Lupus nephritis (LN) is a common immune disease. The microRNA (miR)-181d-
5p is a potential target for treating kidney injury. However, the therapeutic role of miR-181d …
5p is a potential target for treating kidney injury. However, the therapeutic role of miR-181d …
[HTML][HTML] An advanced comprehensive muti-cell-type-specific model for predicting anti-PD-1 therapeutic effect in melanoma
W Sun, Y Zhu, Z Zou, L Wang, J Zhong, K Shen… - Theranostics, 2024 - ncbi.nlm.nih.gov
Rationale: Immune checkpoint inhibitors targeting the programmed cell death (PD)-1/PD-L1
pathway have promise in patients with advanced melanoma. However, drug resistance …
pathway have promise in patients with advanced melanoma. However, drug resistance …
[HTML][HTML] Effect of astrocyte GPER on the optic nerve inflammatory response following optic nerve injury in mice
X Wang, J Zhou, Y Wang, X Li, Q Hu, L Luo, X Liu… - Heliyon, 2024 - cell.com
Activated astrocytes are a primary source of inflammatory factors following traumatic optic
neuropathy (TON). Accumulation of inflammatory factors in this context leads to increased …
neuropathy (TON). Accumulation of inflammatory factors in this context leads to increased …
Exosomal miR‐181d‐5p Derived from Rapamycin‐Conditioned MDSC Alleviated Allograft Rejection by Targeting KLF6
C Wei, Y Sun, F Zeng, X Chen, L Ma, X Liu… - Advanced …, 2023 - Wiley Online Library
Immune rejection and side effects of long‐term administration of immunosuppressants are
the two major obstacles to allograft acceptance and tolerance. The immunosuppressive …
the two major obstacles to allograft acceptance and tolerance. The immunosuppressive …