Non-alcoholic fatty liver disease: metabolic, genetic, epigenetic and environmental risk factors
O Juanola, S Martínez-López, R Francés… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …
Epigenetics of aging and aging-associated diseases
D Saul, RL Kosinsky - International journal of molecular sciences, 2021 - mdpi.com
Aging represents the multifactorial decline in physiological function of every living organism.
Over the past decades, several hallmarks of aging have been defined, including epigenetic …
Over the past decades, several hallmarks of aging have been defined, including epigenetic …
Current options and future directions for NAFLD and NASH treatment
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, with a broad spectrum ranging from simple steatosis to advanced stage of …
worldwide, with a broad spectrum ranging from simple steatosis to advanced stage of …
Diagnostic modalities of non-alcoholic fatty liver disease: from biochemical biomarkers to multi-omics non-invasive approaches
E Martinou, M Pericleous, I Stefanova, V Kaur… - Diagnostics, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …
Epigenetic regulation of energy metabolism in obesity
W Gao, JL Liu, X Lu, Q Yang - Journal of molecular cell biology, 2021 - academic.oup.com
Obesity has reached epidemic proportions globally. Although modern adoption of a
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …
Faecal Microbiota transplantation affects liver DNA methylation in Non-alcoholic fatty liver disease: a multi-omics approach
D Stols-Gonçalves, AL Mak, MS Madsen… - Gut …, 2023 - Taylor & Francis
Individuals with nonalcoholic fatty liver disease (NAFLD) have an altered gut microbiota
composition. Moreover, hepatic DNA methylation may be altered in the state of NAFLD …
composition. Moreover, hepatic DNA methylation may be altered in the state of NAFLD …
DNA 5mC and RNA m6A modification successively facilitates the initiation and perpetuation stages of HSC activation in liver fibrosis progression
Y Feng, S Guo, Y Zhao, H Dong, J Qian, Y Hu… - Cell Death & …, 2023 - nature.com
Hepatic stellate cells (HSC) are key effector cells in liver fibrosis. Upon stimulation, the
quiescent HSC undergoes complex morphological and functional changes to …
quiescent HSC undergoes complex morphological and functional changes to …
Detangling the interrelations between MAFLD, insulin resistance, and key hormones
SC Pal, M Eslam, N Mendez-Sanchez - Hormones, 2022 - Springer
Metabolic dysfunction–associated fatty liver disease (MAFLD) has increasingly become a
significant and highly prevalent cause of chronic liver disease, displaying a wide array of risk …
significant and highly prevalent cause of chronic liver disease, displaying a wide array of risk …
Epigenetic regulation of hepatic lipid metabolism by DNA methylation
While extensive investigations have been devoted to the study of genetic pathways related
to fatty liver diseases, much less is known about epigenetic mechanisms underlying these …
to fatty liver diseases, much less is known about epigenetic mechanisms underlying these …
Epigenetic regulation of peroxisome proliferator-activated receptor gamma mediates high-fat diet-induced non-alcoholic fatty liver disease
T Hajri, M Zaiou, TV Fungwe, K Ouguerram, S Besong - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in Western countries and has
become a serious public health concern. Although Western-style dietary patterns …
become a serious public health concern. Although Western-style dietary patterns …