Linkage disequilibrium—understanding the evolutionary past and mapping the medical future
M Slatkin - Nature Reviews Genetics, 2008 - nature.com
Linkage disequilibrium—the nonrandom association of alleles at different loci—is a sensitive
indicator of the population genetic forces that structure a genome. Because of the explosive …
indicator of the population genetic forces that structure a genome. Because of the explosive …
Alu repeats and human genomic diversity
MA Batzer, PL Deininger - Nature reviews genetics, 2002 - nature.com
During the past 65 million years, Alu elements have propagated to more than one million
copies in primate genomes, which has resulted in the generation of a series of Alu …
copies in primate genomes, which has resulted in the generation of a series of Alu …
Patterns of linkage disequilibrium in the human genome
KG Ardlie, L Kruglyak, M Seielstad - Nature Reviews Genetics, 2002 - nature.com
Particular alleles at neighbouring loci tend to be co-inherited. For tightly linked loci, this
might lead to associations between alleles in the population—a property known as linkage …
might lead to associations between alleles in the population—a property known as linkage …
[图书][B] Human evolutionary genetics: origins, peoples and disease
M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …
together molecular genetics and genomics to the study of the origins and movements of …
The Pattern of Polymorphism in Arabidopsis thaliana
M Nordborg, TT Hu, Y Ishino, J Jhaveri… - PLoS …, 2005 - journals.plos.org
We resequenced 876 short fragments in a sample of 96 individuals of Arabidopsis thaliana
that included stock center accessions as well as a hierarchical sample from natural …
that included stock center accessions as well as a hierarchical sample from natural …
Gene conversion: mechanisms, evolution and human disease
Gene conversion, one of the two mechanisms of homologous recombination, involves the
unidirectional transfer of genetic material from a'donor'sequence to a highly homologous' …
unidirectional transfer of genetic material from a'donor'sequence to a highly homologous' …
High-resolution mapping of meiotic crossovers and non-crossovers in yeast
Meiotic recombination has a central role in the evolution of sexually reproducing organisms.
The two recombination outcomes, crossover and non-crossover, increase genetic diversity …
The two recombination outcomes, crossover and non-crossover, increase genetic diversity …
Haplotype blocks and linkage disequilibrium in the human genome
JD Wall, JK Pritchard - Nature Reviews Genetics, 2003 - nature.com
There is great interest in the patterns and extent of linkage disequilibrium (LD) in humans
and other species. Characterizing LD is of central importance for gene-mapping studies and …
and other species. Characterizing LD is of central importance for gene-mapping studies and …
[PDF][PDF] The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus
E Wang, YC Ding, P Flodman, JR Kidd, KK Kidd… - The American Journal of …, 2004 - cell.com
Associations of the seven-repeat (7R) allele of the human dopamine receptor D4 (DRD4)
gene with both the personality trait of novelty seeking and attention deficit/hyperactivity …
gene with both the personality trait of novelty seeking and attention deficit/hyperactivity …
The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits
JC Florez, J Hirschhorn… - Annual review of genomics …, 2003 - annualreviews.org
Diabetes encompasses a heterogeneous group of diseases, each with a substantial genetic
component. We review the division of diabetes into different subtypes based on clinical …
component. We review the division of diabetes into different subtypes based on clinical …