Chemotherapy side-effects: not all DNA damage is equal

WMC van den Boogaard, DSJ Komninos, WP Vermeij - Cancers, 2022 - mdpi.com
Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …

Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment

J Burgess, M Ferdousi, D Gosal, C Boon… - Oncology and …, 2021 - Springer
Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

Pathomechanisms of paclitaxel-induced peripheral neuropathy

I Klein, HC Lehmann - Toxics, 2021 - mdpi.com
Peripheral neuropathy is one of the most common side effects of chemotherapy, affecting up
to 60% of all cancer patients receiving chemotherapy. Moreover, paclitaxel induces …

Layer-by-layer biomaterials for drug delivery

D Alkekhia, PT Hammond… - Annual review of …, 2020 - annualreviews.org
Controlled drug delivery formulations have revolutionized treatments for a range of health
conditions. Over decades of innovation, layer-by-layer (LbL) self-assembly has emerged as …

Clinical and preclinical perspectives on Chemotherapy-Induced Peripheral Neuropathy (CIPN): a narrative review

SJL Flatters, PM Dougherty… - BJA: British Journal of …, 2017 - academic.oup.com
This review provides an update on the current clinical and preclinical understanding of
chemotherapy induced peripheral neuropathy (CIPN). The overview of the clinical syndrome …

Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy

G Fumagalli, L Monza, G Cavaletti, R Rigolio… - Frontiers in …, 2021 - frontiersin.org
Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Rationalizing the therapeutic potential of apigenin against cancer

SA Ahmed, D Parama, E Daimari, S Girisa, K Banik… - Life sciences, 2021 - Elsevier
Background Despite the remarkable advances made in the diagnosis and treatment of
cancer during the past couple of decades, it remains the second largest cause of mortality in …

A polydopamine-based platform for anti-cancer drug delivery

RS Ambekar, B Kandasubramanian - Biomaterials science, 2019 - pubs.rsc.org
Cancer is the second leading cause of death in the world with around 9.6 million deaths in
2018, approximately 70% of which occurred in the middle-and low-income countries; …

Chemotherapy‐induced peripheral neurotoxicity: A multifaceted, still unsolved issue

G Cavaletti, P Alberti, AA Argyriou… - Journal of the …, 2019 - Wiley Online Library
Chemotherapy‐induced peripheral neurotoxicity (CIPN) is a potentially dose‐limiting side
effect of several commonly used cytotoxic chemotherapy agents. The main pharmacological …

Guidelines for perioperative pain management: need for re-evaluation

GP Joshi, H Kehlet… - BJA: British Journal …, 2017 - academic.oup.com
Local anaesthetics, delivered percutaneously through a needle, have been used for over a
century to provide perioperative anaesthesia and analgesia. However, the duration of a …