Fungi as mediators linking organisms and ecosystems

M Bahram, T Netherway - FEMS Microbiology Reviews, 2022 - academic.oup.com
Fungi form a major and diverse component of most ecosystems on Earth. They are both
micro and macroorganisms with high and varying functional diversity as well as great …

[HTML][HTML] Emerging antifungal targets and strategies

M Ivanov, A Ćirić, D Stojković - International Journal of Molecular …, 2022 - mdpi.com
Despite abundant research in the field of antifungal drug discovery, fungal infections remain
a significant healthcare burden. There is an emerging need for the development of novel …

[HTML][HTML] Ten decadal advances in fungal biology leading towards human well-being

A Mapook, KD Hyde, K Hassan, BM Kemkuignou… - Fungal Diversity, 2022 - Springer
Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …

Quorum sensing in fungal species

X Tian, H Ding, W Ke, L Wang - Annual Review of Microbiology, 2021 - annualreviews.org
Quorum sensing (QS) is one of the most studied cell-cell communication mechanisms in
fungi. Research in the last 20 years has explored various fungal QS systems that are …

A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise

KC Howard, EK Dennis, DS Watt… - Chemical Society …, 2020 - pubs.rsc.org
The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …

[HTML][HTML] Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators

B Hommel, L Mukaremera, RJB Cordero… - PLoS …, 2018 - journals.plos.org
The pathogenic fungus Cryptococcus neoformans exhibits morphological changes in cell
size during lung infection, producing both typical size 5 to 7 μm cells and large titan cells (> …

[HTML][HTML] Palmitic Acid Inhibits the Virulence Factors of Candida tropicalis: Biofilms, Cell Surface Hydrophobicity, Ergosterol Biosynthesis, and Enzymatic Activity

KG Prasath, H Tharani, MS Kumar… - Frontiers in …, 2020 - frontiersin.org
Biofilm is the fortitude of Candida species infections which eventually causes candidiasis in
human. C. tropicalis is one of the predominant Candida species commonly found in systemic …

[HTML][HTML] Divergent Approaches to Virulence in C. albicans and C. glabrata: Two Sides of the Same Coin

M Galocha, P Pais, M Cavalheiro, D Pereira… - International journal of …, 2019 - mdpi.com
Candida albicans and Candida glabrata are the two most prevalent etiologic agents of
candidiasis worldwide. Although both are recognized as pathogenic, their choice of …

Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens?

PV Stuckey, FH Santiago-Tirado - Infection and Immunity, 2023 - Am Soc Microbiol
Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

[HTML][HTML] Recent advances in understanding Candida albicans hyphal growth

RA Arkowitz, M Bassilana - F1000Research, 2019 - ncbi.nlm.nih.gov
Morphological changes are critical for the virulence of a range of plant and human fungal
pathogens. Candida albicans is a major human fungal pathogen whose ability to switch …