Atrial fibrosis with enhanced turnover and deposition of matrix proteins leads to
inhomogeneous atrial electrical conduction and gives rise to electrical reentry circuits …

The Heart Rhythm Society convened a research symposium on December 9–10, 2013, in
Washington, DC, that focused on the prevention of atrial fibrillation (AF) as well as AF …

Calcium is an important second messenger required not only for the excitation-contraction
coupling of the heart but also critical for the activation of cell signaling pathways involved in …

Atrial fibrillation (AF) is the most common sustained arrhythmia in humans. The mechanisms
that govern AF initiation and persistence are highly complex, of dynamic nature, and involve …

Atrial fibrillation (AF) is a very common cardiac arrhythmia with an estimated prevalence of
33.5 million patients globally. It is associated with an increased risk of death, stroke and …

This paper presents a review of the different approaches existing in the literature to detect
and quantify fibrosis in contrast-enhanced magnetic resonance images of the left atrial wall …

Atrial fibrillation (AF) is the most common sustained arrhythmia, but its mechanisms are
poorly understood. Recently, accumulating evidence indicates a link between immune …

Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide, with an unmet
therapeutic need. Fibrotic remodeling, in which collagen-producing atrial fibroblasts play a …

Multiple structural changes are known to occur in a failing heart. Myocyte hypertrophy,
cardiomyocyte apoptosis, interstitial fibrosis, reduced capillary density, and activation of the …

CaMKII is a serine–threonine protein kinase that is abundant in myocardium. Emergent
evidence suggests that CaMKII may play an important role in promoting atrial fibrillation (AF) …