[HTML][HTML] Extracellular vesicles in atherosclerosis and vascular calcification: The versatile non-coding RNAs from endothelial cells and vascular smooth muscle cells

F Yu, Y Duan, C Liu, H Huang, X Xiao, Z He - Frontiers in Medicine, 2023 - ncbi.nlm.nih.gov
Atherosclerosis (AS) is characterized by the accumulation of lipids, fibrous elements, and
calcification in the innermost layers of arteries. Vascular calcification (VC), the deposition of …

[HTML][HTML] Crosstalk between ubiquitin ligases and ncRNAs drives cardiovascular disease progression

JR You, ZJ Wen, JW Tian, XB Lv, R Li, SP Li… - Frontiers in …, 2024 - frontiersin.org
Cardiovascular diseases (CVDs) are multifactorial chronic diseases and have the highest
rates of morbidity and mortality worldwide. The ubiquitin–proteasome system (UPS) plays a …

Identification and screening of potential ACE2 activating peptides from soybean protein isolate hydrolysate against Ang II-induced endothelial dysfunction

M Zhou, T Song, W Li, M Huang, L Zheng… - Journal of Agricultural …, 2023 - ACS Publications
Angiotensin-converting enzyme 2 (ACE2) is a counterregulator against ACE by converting
angiotensin II (Ang II) to Ang-(1–7), and its down-regulation leads to endothelial dysfunction …

Broccoli extracellular vesicles enhance the therapeutic effects and restore the chemosensitivity of 5-fluorouracil on colon cancer

Y Cao, L Hou, M Li, J Zhang, L Wang, C Liu… - Food and Chemical …, 2024 - Elsevier
Broccoli contains an amount of biologically active substances, which bring beneficial effects
on human health. Plant extracellular vesicles have been shown to be novel key factors in …

Soybean-derived antihypertensive hydrolysates attenuate Ang II-induced renal damage by modulating MAPK and NF-κB signaling pathways

T Song, YY Ding, T Zhang, Q Cai, Y Hu, Q Gu, Z Gu - Food & Function, 2024 - pubs.rsc.org
Hypertension-induced kidney injury is considered a vital consequence of long-term and
uncontrolled hypertension, which is commonly associated with an excessive accumulation …

[HTML][HTML] Coinfection of Dermal Fibroblasts by Human Cytomegalovirus and Human Herpesvirus 6 Can Boost the Expression of Fibrosis-Associated MicroRNAs

I Soffritti, M D'Accolti, C Maccari, F Bini, E Mazziga… - Microorganisms, 2023 - mdpi.com
Tissue fibrosis can affect every type of tissue or organ, often leading to organ malfunction;
however, the mechanisms involved in this process are not yet clarified. A role has been …