Glutathione transferase classical GSH conjugation activity plays a critical role in cellular
detoxification against xenobiotics and noxious compounds as well as against oxidative …

An immunosensor is a kind of affinity biosensor based on interactions between an antigen
and specific antigen immobilized on a transducer surface. Immunosensors possess high …

Huntington's disease is characterized by a triad of motor, cognitive and psychiatric
impairments, as well as unintended weight loss. Although much of the research has focused …

Our understanding of lipid peroxidation in biology and medicine is rapidly evolving, as it is
increasingly implicated in various diseases but also recognized as a key part of normal cell …

Abstract Systems medicine is founded on a mechanism-based approach and identifies in
this way specific therapeutic targets. This approach has been applied for the transcription …

Alzheimer's disease (AD), the most common neurodegenerative disorder associated with
dementia, is typified by the pathological accumulation of amyloid Aβ peptides and …

This review provides an overview of the biochemistry of thiol redox couples and the
significance of thiol redox homeostasis in neurodegenerative disease. The discussion is …

Astrocytes are now viewed as key elements of brain wiring as well as neuronal
communication. Indeed, they not only bridge the gap between metabolic supplies by blood …

The ultimate aim of this study is to produce a composite of bimetallic platinum-cobalt
nanoparticles and reduced graphene oxide (Pt-Co@ rGO) based biosensor for the detection …

Despite more than 300 theories to explain the aging process, oxidative stress theory offers
the best mechanism to explain aging and age related disorders. Several studies has shown …