[HTML][HTML] Advances in MALDI mass spectrometry imaging single cell and tissues
X Zhu, T Xu, C Peng, S Wu - Frontiers in Chemistry, 2022 - frontiersin.org
Compared with conventional optical microscopy techniques, mass spectrometry imaging
(MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique …
(MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique …
Mass spectrometry imaging of biomolecular information
B Spengler - Analytical chemistry, 2015 - ACS Publications
Mass spectrometry imaging (MSI) has gone through a significant change over the last 3
years, the time span of this review. The predominant mass spectrometric method in …
years, the time span of this review. The predominant mass spectrometric method in …
[HTML][HTML] Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues
Glycosylation is essential to brain development and function, but prior studies have often
been limited to a single analytical technique and excluded region-and sex-specific analyses …
been limited to a single analytical technique and excluded region-and sex-specific analyses …
Linkage-Specific in Situ Sialic Acid Derivatization for N-Glycan Mass Spectrometry Imaging of Formalin-Fixed Paraffin-Embedded Tissues
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging is a rapidly
evolving field in which mass spectrometry techniques are applied directly on tissues to …
evolving field in which mass spectrometry techniques are applied directly on tissues to …
MALDI mass spectrometry imaging of N-linked glycans in cancer tissues
RR Drake, TW Powers, EE Jones, E Bruner… - Advances in cancer …, 2017 - Elsevier
Glycosylated proteins account for a majority of the posttranslation modifications of cell
surface, secreted, and circulating proteins. Within the tumor microenvironment, the presence …
surface, secreted, and circulating proteins. Within the tumor microenvironment, the presence …
Recent advances in the analysis of complex glycoproteins
Notes 408 Biographies 408 Acknowledgments 409 References 409 The enormous
structural diversity of glycoconjugates mirrors their myriad biological functions in prokaryotic …
structural diversity of glycoconjugates mirrors their myriad biological functions in prokaryotic …
[HTML][HTML] N-glycan MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissue enables the delineation of ovarian cancer tissues
Ovarian cancer is a fatal gynaecological malignancy in adult women with a five-year overall
survival rate of only 30%. Glycomic and glycoproteomic profiling studies have reported …
survival rate of only 30%. Glycomic and glycoproteomic profiling studies have reported …
Advances in mass spectrometry‐based glycomics
The diversification of the chemical properties and biological functions of proteins is attained
through posttranslational modifications, such as glycosylation. Glycans, which are covalently …
through posttranslational modifications, such as glycosylation. Glycans, which are covalently …
On-tissue derivatization with Girard's reagent P enhances N-glycan signals for formalin-fixed paraffin-embedded tissue sections in MALDI mass spectrometry imaging
Glycosylation is a major protein post-translational modification whose dysregulation has
been associated with many diseases. Herein, an on-tissue chemical derivatization strategy …
been associated with many diseases. Herein, an on-tissue chemical derivatization strategy …
N-linked glycan branching and fucosylation are increased directly in Hcc tissue as determined through in situ glycan imaging
CA West, M Wang, H Herrera, H Liang… - Journal of proteome …, 2018 - ACS Publications
Hepatocellular carcinoma (HCC) remains as the fifth most common cancer in the world and
accounts for more than 700,000 deaths annually. Changes in serum glycosylation have long …
accounts for more than 700,000 deaths annually. Changes in serum glycosylation have long …