Taking your breath away: metabolomics breathes life in to personalized medicine
Breath-based metabolomics (breathomics) is an exciting developing area of biotechnology
that centers on the capture, identification, and quantification of volatile organic compound …
that centers on the capture, identification, and quantification of volatile organic compound …
Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine
Chronic obstructive pulmonary disease (COPD) is a complex disease at the clinical, cellular,
and molecular levels. However, its diagnosis, assessment, and therapeutic management are …
and molecular levels. However, its diagnosis, assessment, and therapeutic management are …
Exhaled air molecular profiling in relation to inflammatory subtype and activity in COPD
N Fens, SB de Nijs, S Peters, T Dekker… - European …, 2011 - Eur Respiratory Soc
Eosinophilic inflammation in chronic obstructive pulmonary disease (COPD) is predictive for
responses to inhaled steroids. We hypothesised that the inflammatory subtype in mild and …
responses to inhaled steroids. We hypothesised that the inflammatory subtype in mild and …
[HTML][HTML] Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma
A pathological hallmark of asthma is chronic injury and repair, producing dysfunction of the
epithelial barrier function. In this setting, increased oxidative stress, growth factor-and …
epithelial barrier function. In this setting, increased oxidative stress, growth factor-and …
Survey of the 2009 commercial optical biosensor literature
RL Rich, DG Myszka - Journal of Molecular Recognition, 2011 - Wiley Online Library
We took a different approach to reviewing the commercial biosensor literature this year by
inviting 22 biosensor users to serve as a review committee. They set the criteria for what to …
inviting 22 biosensor users to serve as a review committee. They set the criteria for what to …
Quantitative validation and comparison of multiplex cytokine kits
JL Richens, RA Urbanowicz, R Metcalf… - Journal of …, 2010 - journals.sagepub.com
The focus of biomarker studies is shifting toward deciphering patterns of biomolecules as
they provide a more comprehensive depiction of disease than individual biomarkers …
they provide a more comprehensive depiction of disease than individual biomarkers …
[图书][B] Nanoscopy and multidimensional optical fluorescence microscopy
A Diaspro - 2010 - taylorfrancis.com
" Alberto Diaspro has been choreographing light's dance for over 20 years, and in
Nanoscopy and Multidimensional Optical Fluorescence Microscopy, he has assembled a …
Nanoscopy and Multidimensional Optical Fluorescence Microscopy, he has assembled a …
Protein networks in induced sputum from smokers and COPD patients
JN Baraniuk, B Casado, LK Pannell… - … journal of chronic …, 2015 - Taylor & Francis
Rationale Subtypes of cigarette smoke-induced disease affect different lung structures and
may have distinct pathophysiological mechanisms. Objective To determine if proteomic …
may have distinct pathophysiological mechanisms. Objective To determine if proteomic …
Fluctuation analysis of peak expiratory flow and its association with treatment failure in asthma
Rationale: Temporal fluctuations have been demonstrated in lung function and asthma
control, but the effect of controller therapy on these fluctuations is unknown. Objectives: To …
control, but the effect of controller therapy on these fluctuations is unknown. Objectives: To …
Avoiding nonspecific interactions in studies of the plasma proteome: practical solutions to prevention of nonspecific interactions for label-free detection of low …
JL Richens, EAM Lunt, D Sanger… - Journal of Proteome …, 2009 - ACS Publications
The molecular constitution of blood can be highly representative of the physiological state of
an individual and offers an ideal target for studies of biomarkers. High-abundance plasma …
an individual and offers an ideal target for studies of biomarkers. High-abundance plasma …