DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Recent advances in cell-type deconvolution approaches are adding to our understanding of
the biology underlying disease development and progression. DNA methylation (DNAm) …

Epigenetics refers to mitotically heritable changes to the DNA, which do not affect the DNA
sequence, but can influence its function. Currently, DNA methylation is the most studied …

Background: Several studies have shown effects of current and maternal smoking during
pregnancy on DNA methylation of CpG sites in newborns and later in life. Here, we …

Background Prenatal smoke exposure is known to be robustly associated with DNA
methylation among offspring in early life, but whether the association persists into adulthood …

It is thought that germ cells and preimplantation embryos during development are most
susceptible to endogenous and exogenous environmental factors because the epigenome …

In utero exposure to maternal tobacco smoking is the leading cause of birth complications in
addition to being associated with later impairment in child's development. Epigenetic …

COPD, characterized by long-term poorly irreversible airway limitation and persistent
respiratory symptoms, has resulted in enormous challenges to human health worldwide …

Adiposity and obesity result from the interaction of genetic variation and environmental
factors from very early in life, possibly mediated by epigenetic processes. Few Epigenome …

Depression is a severe and debilitating mental disorder diagnosed by evaluation of
affective, cognitive and physical depression symptoms. Severity of these symptoms strongly …