Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies,
especially related to the lack of recombination, to a high copy number, and to matrilineal …

Mosquitoes' importance as vectors of pathogens that drive disease underscores the
importance of precise and comparable methods of taxa identification among their species …

Mitochondrial DNA (mtDNA) profiles can be classified into phylogenetic clusters
(haplogroups), which is of great relevance for evolutionary, forensic and medical genetics …

Human DNA profiling using PCR at polymorphic short tandem repeat (STR) loci followed by
capillary electrophoresis (CE) size separation and length-based allele typing has been the …

Background Although high-throughput sequencers (HTS) have largely displaced their
Sanger counterparts, the short read lengths and high error rates of most platforms constrain …

Within-species contamination is a major issue in sequencing studies, especially for
mitochondrial studies. Contamination can be detected by analyzing the nuclear genome or …

The mitochondrial genome (mtDNA) represents a tiny fraction of the whole genome,
comprising just 16.6 kilobases encoding 37 genes involved in oxidative phosphorylation …

As a first step towards integrating next generation sequencing (NGS) technology into the FBI
Laboratory's operational casework, the PowerSeq™ CRM Nested System, an NGS-based …

Mitochondria from normal and cancerous cells represent a tale of two cities, wherein both
execute similar processes but with different cellular and molecular effects. Given the number …

Nuclear mitochondrial DNA (mtDNA) segments (NUMTs) were discovered shortly after
sequencing the first human mitochondrial genome. They have earlier been considered to …