The high affinity and specificity of peptides towards biological targets, in addition to their
favorable pharmacological properties, has encouraged the development of many peptide …

Receptor-based radiopharmaceuticals are of great current interest in molecular imaging and
radiotherapy of cancers, and provide a unique tool for target-specific delivery of …

Human cancer cells overexpress many peptide receptors as molecular targets.
Radiolabeled peptides that bind with high affinity and specificity to the receptors on tumor …

The detection of cell-bound proteins that are produced due to aberrant gene expression in
malignant tumors can provide important diagnostic information influencing patient …

Immunotherapy has become a promising alternative therapeutic approach for cancer
patients. Interruption of immune checkpoints, such as CTLA-4 and PD-1, has been verified to …

Accurate and rapid detection of tumors is of great importance for interrogating the molecular
basis of cancer pathogenesis, preventing the onset of complications, and implementing a …

Blockade of the immune checkpoint PD-1/PD-L1 with monoclonal antibodies demonstrated
unprecedented clinical efficacies in many cancers. But the orally available low molecular …

Radiolabeled peptides are of increasing interest in nuclear oncology. Special emphasis has
been given to the development of peptides labeled with positron emitters. Among these, 68 …

New peptide-based probes to facilitate the molecular imaging of disease are rapidly
evolving due to implementation of combinatorial chemistry and bacteriophage (phage) …

Endothelial cells (EC) of angiogenic tumor vasculature are characterized by altered
expression of molecular markers on their surface. Numerous peptides have been identified …