The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Increasing oxidative stress, a major characteristic of aging, has been implicated in a variety
of age-related pathologies. In aging, oxidant production from several sources is increased …

Oxidative stress due to imbalance between ROS production and detoxification plays a
pivotal role in determining cell fate. In response to the excessive ROS, apoptotic signaling …

Hutchinson-Gilford progeria syndrome (HGPS) is a rare, invariably fatal premature aging
disorder. The disease is caused by constitutive production of progerin, a mutant form of the …

The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and
photoprotective effects on the skin. These are achieved through immunomodulation and …

Redox homeostasis is maintained by the antioxidant defense system, which is responsible
for eliminating a wide range of oxidants, including reactive oxygen species (ROS), lipid …

Hesperidin is a bioflavonoid, with high concentration in citrus fruits. In addition to its well‐
known benefits for cardiovascular function, type II diabetes, and anti‐inflammation, recent …

The resident prokaryotic microbiota of the mammalian intestine influences diverse
homeostatic functions, including regulation of cellular growth, maintenance of barrier …

The skin is frequently exposed to environmental challenges, such as UV irradiation, toxic
chemicals, and mechanical wounding. These insults cause an increase in the levels of …

The olive-oil-centered Mediterranean diet has been associated with extended life
expectancy and a reduction in the risk of age-related degenerative diseases. Extra virgin …