The increased prevalence of obesity presents challenges for clinicians aiming to provide
optimised antimicrobial dosing in the intensive care unit. Obesity is likely to exacerbate the …

OBJECTIVE: β-lactams are the cornerstone of empiric and targeted antibiotic therapy for
critically ill patients. Recently, there have been calls to use β-lactam therapeutic drug …

Polymyxin B is an effective but potentially nephrotoxic antibiotic that is commonly used to
treat resistant Gram-negative infections. As a weight-based dosing drug, obese patients may …

Objectives The objectives of this study were to determine the effects of obesity on unbound
trough concentrations and on the achievement of pharmacokinetic (PK)/pharmacodynamic …

While suboptimal dosing of antimicrobials has been attributed to poorer clinical outcomes,
clinical cure and mortality advantages have been demonstrated when target …

Vancomycin dosing in an obese patient with acute renal failure: A case report and review of
literature - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Inleiding: Het aantal ziekenhuisopnames op intensieve zorg (IZ) van patiënten met als
comorbiditeit obesitas stijgt. Het instellen van een adequate dosering van anti-infectieuze …

The increasing numbers of critically ill obese patients in the intensive care unit (ICU) and the
high frequency of antimicrobial prescription in these patients present a challenge for …