Background Recommendations for improved survival after cancer through physical activity
(PA) exist, although the evidence is still emerging. Our primary objective was to conduct a …

There is increasing interest in applying a precision medicine approach to understanding
exercise as a potential treatment for cancer. We aimed to inform this new approach by …

The integrity and composition of the tumour microenvironment (TME) is highly plastic,
undergoing constant remodelling in response to instructive signals derived from alterations …

Exercise is recognized by clinicians in the field of clinical oncology for its potential role in
reducing the risk of certain cancers and in reducing the risk of disease recurrence and …

A major objective of the emerging field of exercise–oncology research is to determine the
efficacy of, and biological mechanisms by which, aerobic exercise affects cancer incidence …

Natural killer (NK) cells are the most responsive immune cells to exercise, displaying an
acute mobilization to the circulation during physical exertion. Recently, exercise-dependent …

Exercise training has been extensively studied in cancer settings as part of prevention or
rehabilitation strategies, yet emerging evidence suggests that exercise training can also …

Importance Adult survivors of childhood cancer are at excess risk for mortality compared with
the general population. Whether exercise attenuates this risk is not known. Objective To …

Approximately 40% of men and women in the United States will be diagnosed with cancer at
some point in their lives. There have been dramatic developments in our understanding of …

Pharmacologic manipulation of the immune system is emerging as a viable and robust
treatment for some cancer patients. Exercise-induced modulation of the immune system may …