The NF-κB family of dimeric transcription factors regulate diverse biological functions. Their
cellular expression profiles differ, which lead to different concentrations in different …

Aim: CCL20, also known as MIP-3 alpha, is a chemokine that participates in chemotaxis of
immature dendritic cells, effector/memory T-cells, and B-lymphocytes. The objectives of this …

Overexpression of the low molecular–weight isoforms (LMW-E) of cyclin E induces
chromosome instability; however, the degree to which these tumor-specific forms cause …

The noncanonical NFκB signaling pathway mediates the biological functions of diverse cell
survival, growth, maturation, and differentiation factors that are important for the …

Helicobacter pylori causes various gastroduodenal diseases including gastric MALT
lymphoma, but the mechanism underlying H. pylori-induced carcinogenesis is not known …

Abstract Indoleamine 2, 3‐dioxygenase (IDO) is the rate‐limiting enzyme in the kynurenine
(Kyn) pathway of tryptophan (Trp) metabolism. IDO is immunosuppressive and is induced by …

The NF-κB transcription factor mediates the inflammatory response through distinct
(canonical and non-canonical) signaling pathways. The mechanisms controlling utilization …

Previous studies have demonstrated that peptides corresponding to a six-amino-acid NEMO-
binding domain from the C terminus of IκB kinase alpha (IKKα) and IKKβ can disrupt the IKK …

The transcription factor NF-κB controls key features of hair follicle (HF) development, but the
role of NF-κB in adult HF cycle regulation remains obscure. Using NF-κB reporter mouse …

NF-κB is a family of essential transcription factors involved in both embryonic development
and inflammatory responses of the immune system. NF-κB can be activated by two …