[HTML][HTML] New opportunities and challenges of natural products research: When target identification meets single-cell multiomics
Y Zhu, Z Ouyang, H Du, M Wang, J Wang, H Sun… - … Pharmaceutica Sinica B, 2022 - Elsevier
Natural products, and especially the active ingredients found in traditional Chinese medicine
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …
[HTML][HTML] Marine natural products in clinical use
Marine natural products are potent and promising sources of drugs among other natural
products of plant, animal, and microbial origin. To date, 20 drugs from marine sources are in …
products of plant, animal, and microbial origin. To date, 20 drugs from marine sources are in …
CMNPD: a comprehensive marine natural products database towards facilitating drug discovery from the ocean
Marine organisms are expected to be an important source of inspiration for drug discovery
after terrestrial plants and microorganisms. Despite the remarkable progress in the field of …
after terrestrial plants and microorganisms. Despite the remarkable progress in the field of …
Natural products as inspiration for the development of bacterial antibiofilm agents
Natural products have historically been a rich source of diverse chemical matter with
numerous biological activities, and have played an important role in drug discovery in many …
numerous biological activities, and have played an important role in drug discovery in many …
Accelerating drug discovery: synthesis of complex chemotypes via multicomponent reactions
MJ Buskes, A Coffin, DM Troast, R Stein… - ACS Medicinal …, 2023 - ACS Publications
The generation of multiple bonds in one reaction step has attracted massive interest in drug
discovery and development. Multicomponent reactions (MCRs) offer the advantage of …
discovery and development. Multicomponent reactions (MCRs) offer the advantage of …
[HTML][HTML] The intriguing chemistry and biology of sulfur-containing natural products from marine microorganisms (1987–2020)
Natural products derived from marine microorganisms have received great attention as a
potential resource of new compound entities for drug discovery. The unique marine …
potential resource of new compound entities for drug discovery. The unique marine …
Enriching cancer pharmacology with drugs of marine origin
Marine natural products have proven, over the last half‐century, to be effective biological
modulators. These molecules have revealed new targets for cancer therapy as well as …
modulators. These molecules have revealed new targets for cancer therapy as well as …
[HTML][HTML] Comprehensive virtual screening of the antiviral potentialities of marine polycyclic guanidine alkaloids against SARS-CoV-2 (COVID-19)
The huge global expansion of the COVID-19 pandemic caused by the novel SARS-corona
virus-2 is an extraordinary public health emergency. The unavailability of specific treatment …
virus-2 is an extraordinary public health emergency. The unavailability of specific treatment …
Marine natural products as source of new drugs: A patent review (2015–2018)
P Shinde, P Banerjee, A Mandhare - Expert opinion on therapeutic …, 2019 - Taylor & Francis
Introduction: Natural products from plants, animals, microbes, and minerals have long been
a traditional source for the treatment of human diseases. In the past decades, research on …
a traditional source for the treatment of human diseases. In the past decades, research on …
A propitious role of marine sourced polysaccharides: Drug delivery and biomedical applications
Numerous compounds, with extensive applications in biomedical and biotechnological
fields, are present in the oceans, which serve as a prime renewable source of natural …
fields, are present in the oceans, which serve as a prime renewable source of natural …