The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Asthma is a heterogenous chronic inflammatory lung disease with endotypes that manifest
different immune system profiles, severity, and responses to current therapies. Regardless of …

Platycodon grandiflorus (Jacq.) A. DC.(PG) root is one of the most commonly used medicine-
food materials for respiratory discomfort in Asia, usually in the form of a decoction or …

Chronic respiratory diseases and infections are among the largest contributors to death
globally, many of which still have no cure, including chronic obstructive pulmonary disorder …

The aim of this study was to explore the effects of spray cryotherapy (SCT) on cough
receptors and airway microenvironment in a canine model of chronic bronchitis. We …

Resident tissue macrophages are organ-specialized phagocytes responsible for the
maintenance and protection of tissue homeostasis. It is well established that tissue diversity …

Purpose Corticosteroid insensitivity has become a major barrier in the treatment of chronic
obstructive pulmonary disease (COPD). It is known that oxidative stress reduces the …

Highlights What are the main findings? BromAc is a better mucolytic compared to bromelain
or N-acetylcysteine alone. BromAc reduces the viscosity and increases the flow rate of …

It is estimated that more than one-third of people aged over 16 reported living with
inflammation-related chronic illness. Fucoidan, sulfated polysaccharide, has been proven to …

Introduction Chronic bronchitis (CB), a phenotype of chronic obstructive pulmonary disease
(COPD) characterised by persistent cough and mucus hypersecretion, is associated with …