[HTML][HTML] pH-responsive nanocarriers in cancer therapy

NM AlSawaftah, NS Awad, WG Pitt, GA Husseini - Polymers, 2022 - mdpi.com
A number of promising nano-sized particles (nanoparticles) have been developed to
conquer the limitations of conventional chemotherapy. One of the most promising methods is …

Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: Stimuli-responsive carriers, co-delivery and suppressing resistance

M Ashrafizadeh, H Saebfar, MH Gholami… - Expert opinion on …, 2022 - Taylor & Francis
Introduction The application of doxorubicin (DOX) in cancer therapy has been limited due to
its drug resistance and poor internalization. Graphene oxide (GO) nanostructures have the …

[HTML][HTML] Non-melanoma skin cancers: Physio-pathology and role of lipid delivery systems in new chemotherapeutic treatments

EB Souto, R da Ana, V Vieira, JF Fangueiro… - Neoplasia, 2022 - Elsevier
Non-melanoma carcinoma has high incidence rates and has two most common subtypes:
basal cell carcinoma and squamous cell carcinoma. This type of carcinoma is usually not …

Doxorubicin-loaded micelles in tumor cell-specific chemotherapy

YQ Almajidi, MM Kadhim, F Alsaikhan, AT Jalil… - Environmental …, 2023 - Elsevier
Nanomedicine is a field that combines biology and engineering to improve disease
treatment, particularly in cancer therapy. One of the promising techniques utilized in this …

Biofilm microenvironment-responsive polymeric CO releasing micelles for enhanced amikacin efficacy

Q Zhou, T Wang, K Li, S Zhang, K Wang… - Journal of Controlled …, 2023 - Elsevier
Biofilm-associated infections (BAI) have posed serious threats to public health. Novel
therapy based on carbon monoxide (CO) is being increasingly appreciated. However, CO …

Co-delivery of doxorubicin and paclitaxel by reduction/pH dual responsive nanocarriers for osteosarcoma therapy

Y Li, H Hou, P Zhang, Z Zhang - Drug delivery, 2020 - Taylor & Francis
Nanoparticle-based drug delivery system offers a promising platform for combination cancer
therapy. However, the inefficient drug release in cells reduces the therapeutic efficacy of …

[HTML][HTML] Evaluation of pH-sensitive polymeric micelles using citraconic amide bonds for the co-delivery of paclitaxel, etoposide, and rapamycin

MJ Jo, HJ Shin, MS Yoon, SY Kim, CE Jin, CW Park… - Pharmaceutics, 2023 - mdpi.com
Paclitaxel (PTX), etoposide (ETP), and rapamycin (RAPA) have different mechanisms,
allowing multiple pathways to be targeted simultaneously, effectively treating various …

[HTML][HTML] Nanoaggregates of Biphilic Carboxyl-Containing Copolymers as Carriers for Ionically Bound Doxorubicin

AA Artyukhov, AM Nechaeva, MI Shtilman… - Materials, 2022 - mdpi.com
Application of nanocarriers for drug delivery brings numerous advantages, allowing both
minimization of side effects common in systemic drug delivery and improvement in targeting …

ROS-responsive prodrug micelle co-delivery system for synergistic antiatherosclerotic therapy

Q Tang, Y Chen, Y Zhang, K Wang, L Liu… - Molecular …, 2023 - ACS Publications
Tanshinone IIA (TS-IIA) and salvianic acid A (SAA) are the main pharmacological active
constituents of Danshen, which exhibit potent effects on atherosclerosis. A combination of …

pH/redox-responsive core cross-linked based prodrug micelle for enhancing micellar stability and controlling delivery of chemo drugs: An effective combination drug …

HT Gebrie, KD Addisu, HF Darge, YS Birhan… - Biomaterials …, 2022 - Elsevier
Core-crosslinking of micelles (CCMs) appears to be a favorable strategy to enhance micellar
stability and sustained release of the loaded drug. In this study, the DOX-conjugated pH …