Sulfur (S VI) based moieties, especially, the sulfonyl or sulfonamide based analogues have
showed a variety of pharmacological properties, and its derivatives propose a high degree …

Acetylcholine (ACh) has a crucial role in the peripheral and central nervous systems. The
enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl …

Sleep disturbances and cognitive impairment are common in older adults. Mounting
evidence points to a potential connection between sleep and cognitive function. Findings …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Individuals with Down syndrome (DS) commonly possess unique neurocognitive and
neurobehavioral profiles that emerge within specific developmental periods. These profiles …

Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

At present more than 250 FDA approved chlorine containing drugs were available in the
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …

There is considerable debate whether Alzheimer's disease (AD) originates in basal
forebrain or entorhinal cortex. Here we examined whether longitudinal decreases in basal …

The complement system is part of the innate immune response responsible for removing
pathogens and cellular debris, in addition to helping to refine CNS neuronal connections via …

The basal forebrain cholinergic complex comprising medial septum, horizontal and vertical
diagonal band of Broca, and nucleus basalis of Meynert provides the mayor cholinergic …