Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides

G Lach, H Schellekens, TG Dinan, JF Cryan - Neurotherapeutics, 2018 - Elsevier
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Physical exercise in major depression: reducing the mortality gap while improving clinical outcomes

M Belvederi Murri, P Ekkekakis, M Magagnoli… - Frontiers in …, 2019 - frontiersin.org
Major depression shortens life while the effectiveness of frontline treatments remains
modest. Exercise has been shown to be effective both in reducing mortality and in treating …

Altered gut and adipose tissue hormones in overweight and obese individuals: cause or consequence?

MEJ Lean, D Malkova - International journal of obesity, 2016 - nature.com
The aim of this article is to review the research into the main peripheral appetite signals
altered in human obesity, together with their modifications after body weight loss with diet …

Effects of exercise intensity on plasma concentrations of appetite-regulating hormones: Potential mechanisms

TJ Hazell, H Islam, LK Townsend, MS Schmale… - Appetite, 2016 - Elsevier
The physiological control of appetite regulation involves circulating hormones with
orexigenic (appetite-stimulating) and anorexigenic (appetite-inhibiting) properties that …

Does habitual physical activity increase the sensitivity of the appetite control system? A systematic review

K Beaulieu, M Hopkins, J Blundell, G Finlayson - Sports Medicine, 2016 - Springer
Background It has been proposed that habitual physical activity improves appetite control;
however, the evidence has never been systematically reviewed. Objective To examine …

Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signalling and obesity

LE Pritchard, AV Turnbull, A White - Journal of Endocrinology, 2002 - joe.bioscientifica.com
In this study, two experiments were performed, the first of which examined the ovarian
response in ewes that were subject to unilateral ovariectomy (ULO) at different intervals (0 …

Homeostatic and non-homeostatic appetite control along the spectrum of physical activity levels: An updated perspective

K Beaulieu, M Hopkins, J Blundell, G Finlayson - Physiology & behavior, 2018 - Elsevier
The current obesogenic environment promotes physical inactivity and food consumption in
excess of energy requirements, two important modifiable risk factors influencing energy …

The impact of physical activity on food reward: Review and conceptual synthesis of evidence from observational, acute, and chronic exercise training studies

K Beaulieu, P Oustric, G Finlayson - Current obesity reports, 2020 - Springer
Abstract Purpose of Review This review brings together current evidence from
observational, acute, and chronic exercise training studies to inform public debate on the …

Obesity, appetite, and the prefrontal cortex

ME Gluck, P Viswanath, EJ Stinson - Current obesity reports, 2017 - Springer
Abstract Purpose of Review Obesity is a chronic illness and its prevalence is growing
worldwide and numerous factors play a role in the regulation of food intake. The prefrontal …