Recent advances in the design, development, and targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy

MW Amjad, P Kesharwani, MCIM Amin… - Progress in polymer …, 2017 - Elsevier
Small interfering RNA (siRNA) is a relatively novel nucleic acid-based therapy to treat
diseases such as cancer. Nevertheless, substantial obstacles to its clinical applications have …

Spiropyran-based drug delivery systems

A Fagan, M Bartkowski, S Giordani - Frontiers in Chemistry, 2021 - frontiersin.org
Nanocarriers are rapidly growing in popularity in the field of drug delivery. The ability of
nanocarriers to encapsulate and distribute poorly soluble drugs while minimising their …

Temperature-responsive polymeric micelles for optimizing drug targeting to solid tumors

J Akimoto, M Nakayama, T Okano - Journal of controlled release, 2014 - Elsevier
Targeting to solid tumors is the most challenging issue in the drug delivery field. To obtain
the ideal pharmacodynamics of administrated drugs, drug carriers must suppress drug …

A new two‐photon‐sensitive block copolymer nanocarrier

J Babin, M Pelletier, M Lepage, JF Allard… - Angewandte Chemie …, 2009 - Wiley Online Library
Easily disrupted: Micelles of a new amphiphilic block copolymer that bear coumarin groups
are sensitive to near infrared light by two‐photon absorption of the chromophore. Disruption …

Light‐responsive biomaterials: development and applications

JS Katz, JA Burdick - Macromolecular bioscience, 2010 - Wiley Online Library
Novel biomaterials are beneficial to the growing fields of drug delivery, cell biology, micro‐
devices, and tissue engineering. With recent advances in chemistry and materials science …

Design of multifunctional micelle for tumor‐targeted intracellular drug release and fluorescent imaging

W Wang, D Cheng, F Gong, X Miao, X Shuai - Advanced Materials, 2011 - infona.pl
A novel multifunctional polymeric micelle bearing a pH‐tunable on‐off module for
programmed drug release, folate for tumor targeting, and quantum dots for fluorescent …

Enzyme sensitive synthetic polymer micelles based on the azobenzene motif

J Rao, A Khan - Journal of the American Chemical Society, 2013 - ACS Publications
In this study, we investigate the potential of an artificial structural motif, azobenzene, in the
preparation of enzyme sensitive polymeric nanostructures. For this purpose, an azobenzene …

[HTML][HTML] Wavelength controlled photocleavage for orthogonal and sequential release of multiple proteins

MA Azagarsamy, KS Anseth - Angewandte Chemie (International …, 2013 - ncbi.nlm.nih.gov
On-demand manipulation of protein release to alter cellular phenotypes in real time is of
great interest to the fields of drug delivery, tissue engineering and regenerative medicine.[1 …

Smart chemistry in polymeric nanomedicine

R Tong, L Tang, L Ma, C Tu, R Baumgartner… - Chemical Society …, 2014 - pubs.rsc.org
This review provides an overview of smart chemistry developed and utilized in the last 5–10
years in polymer-based drug delivery nanomedicine. Smart chemistry not only facilitates the …

Ultraviolet light-mediated drug delivery: Principles, applications, and challenges

A Barhoumi, Q Liu, DS Kohane - Journal of Controlled Release, 2015 - Elsevier
UV light has been extensively employed in drug delivery because of its versatility, ease of
manipulation, and ability to induce chemical changes on the therapeutic carrier. Here we …