The major development of the past decade in the first-line treatment of recurrent and/or
metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) was the …

Human papillomaviruses (HPVs) are small double‐stranded circular DNA viruses with 8 kb
genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have …

Squamous cell carcinoma in the head and neck (HNSCC) is a common yet poorly
understood cancer, with adverse clinical outcomes due to treatment resistance, recurrence …

The fibroblast growth factor 19 gene FGF19 has previously been reported to be amplified in
several cancer types and encodes for a key autocrine signaler known to promote …

Simple Summary Oral squamous cell carcinoma (OSCC) is one of the most common
smoking-related cancer types in the world. Better understanding of the pathophysiology of …

The possibility to enhance drug delivery by using ultrasound in combination with
microbubbles (USMB) is extensively studied. So far, these studies have focused on the …

Background/Aim: This Japanese multiple-center retrospective study aimed to examine the
real-world treatment outcomes of the EXTREME regimen as a first-line therapy for …

Background: Recurrent locally advanced or metastatic head and neck squamous cell
carcinoma (HNSCC) is associated with dismal prognosis because of its highly invasive …

Aim The aims of the study are to evaluate the clinical outcomes of first-line treatment with
platinum-based chemotherapy and cetuximab in patients with relapsing/metastatic head and …

Background In patients with recurrent or metastatic head and neck squamous cell carcinoma
(R/M HNSCC) the estimated prognosis is usually poor. Patient-specific factors that affect …