The interactions and communications in tumor resistance to radiotherapy: Therapy perspectives
Tumor microenvironment (TME) includes a wide range of cell types including cancer cells,
cells which are involved in stromal structure and immune cells (tumor suppressor and tumor …
cells which are involved in stromal structure and immune cells (tumor suppressor and tumor …
Hijacked immune cells in the tumor microenvironment: molecular mechanisms of immunosuppression and cues to improve T cell-based immunotherapy of solid …
The understanding of the tumor microenvironment (TME) has been expanding in recent
years in the context of interactions among different cell types, through direct cell–cell …
years in the context of interactions among different cell types, through direct cell–cell …
Systems immunology of regulatory T cells: can one circuit explain it all?
S Tripathi, JS Tsang, K Park - Trends in Immunology, 2023 - cell.com
Regulatory T (Treg) cells play vital roles in immune homeostasis and response, including
discrimination between self-and non-self-antigens, containment of immunopathology, and …
discrimination between self-and non-self-antigens, containment of immunopathology, and …
Lrig1-expression confers suppressive function to CD4+ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis
JS Moon, CC Ho, JH Park, K Park, BY Shin… - Nature …, 2023 - nature.com
Regulatory T cells (Treg) are CD4+ T cells with immune-suppressive function, which is
defined by Foxp3 expression. However, the molecular determinants defining the …
defined by Foxp3 expression. However, the molecular determinants defining the …
The multifaceted role of regulatory T cells in breast cancer
K Kos, KE de Visser - Annual review of cancer biology, 2021 - annualreviews.org
The microenvironment of breast cancer hosts a dynamic cross talk between diverse players
of the immune system. While cytotoxic immune cells are equipped to control tumor growth …
of the immune system. While cytotoxic immune cells are equipped to control tumor growth …
CD27 expression on Treg cells limits immune responses against tumors
S Muth, A Klaric, M Radsak, H Schild… - Journal of Molecular …, 2022 - Springer
Regulatory T cells (Tregs) suppress immune responses and thus contribute to immune
homeostasis. On the downside, Tregs also limit immune responses against tumors …
homeostasis. On the downside, Tregs also limit immune responses against tumors …
Immune Cycle‐Based Strategies for Cancer Immunotherapy
Y Li, X Liu, X Zhang, W Pan, N Li… - Advanced Functional …, 2021 - Wiley Online Library
The immune system is composed of immune organs, immune cells, and immunoactive
substances, which plays a vital role in antitumor immunity in cancer immunotherapy. During …
substances, which plays a vital role in antitumor immunity in cancer immunotherapy. During …
Spatial immune heterogeneity of hypoxia-induced exhausted features in high-grade glioma
AR Kim, SJ Choi, J Park, M Kwon, T Chowdhury… - …, 2022 - Taylor & Francis
The tumor immune microenvironment (TIME) in high-grade glioma (HGG) exhibits high
spatial heterogeneity. Though the tumor core and peripheral regions have different …
spatial heterogeneity. Though the tumor core and peripheral regions have different …
Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast …
The clinical successes of immune checkpoint blockade (ICB) in advanced cancer patients
have recently spurred the clinical implementation of ICB in the neoadjuvant and …
have recently spurred the clinical implementation of ICB in the neoadjuvant and …
[HTML][HTML] Intratumoral density of regulatory T cells is a predictor of host immune response and chemotherapy response in colorectal cancer
Regulatory T cells (Tregs) are a subset of CD4+ T lymphocytes known to dampen the host
immune response against cancer cells. Within the tumor microenvironment, Tregs are potent …
immune response against cancer cells. Within the tumor microenvironment, Tregs are potent …