Despite the existence of extensive clinical research and novel therapeutic treatments,
cancer remains undefeated and the significant cause of death worldwide. Cancer is a …

Prostate cancer remains one of the leading causes of cancer death in men worldwide. In the
past decade, several new treatments for advanced prostate cancer have been approved …

MicroRNAs (miRNAs) play an important role in the biological process. Their expression and
functional changes have been observed in most cancers. Meanwhile, there exists …

The reduction in androgen synthesis and the blockade of the androgen receptor (AR)
function by chemical castration and AR signaling inhibitors represent the main treatment …

Prostate cancer belongs in the class of hormone-dependent cancers, representing a major
cause of cancer incidence in men worldwide. Since upon disease onset almost all prostate …

Breast cancer (BC) and prostate cancer (PC) are at the top of the list when it comes to the
most common types of cancers worldwide. The phosphatidylinositol 3-kinase (PI3K)/protein …

Castration-resistant prostate cancer, or CRPC, is an aggressive stage of prostate cancer
(PCa) in which PCa cells invade nearby or other parts of the body. When a patient with PCa …

Prostate cancer (PCa) is one of the most common malignancies among men worldwide.
Inevitably, all advanced PCa patients develop metastatic castration-resistant prostate cancer …

The dysregulation of the phosphatidylinositol-3-kinase (PI3K) pathway can lead to
uncontrolled cellular growth and tumorigenesis. Targeting PI3K and its downstream …

Prostate cancer (PCa) is today the second most common cancer in the world, with almost
400,000 deaths annually. Multiple factors are involved in the etiology of PCa, such as older …