Background Pediatric medullary thyroid cancer (MTC) is one of the rare pediatric endocrine
neoplasms. Derived from C cells of thyroid glands, MTC is more aggressive and more …

Background Early‐stage lung adenocarcinoma that radiologically manifests as part‐solid
nodules, consisting of both ground‐glass and solid components, has distinctive growth …

Adrenal glands, vital for steroid secretion and the regulation of metabolism, stress responses
and immune activation, experience age-related decline, impacting systemic health …

In the quest to advance neuroblastoma therapeutics, there is a need to have a deeper
understanding of the tumor microenvironment (TME). From extracellular matrix proteins to …

In this letter, we re-analyze human fetal adrenal data generated by Dong et al. to
demonstrate the pitfalls of relying on mouse marker genes to annotate human data. We …

Background: Neuroblastoma (NB) is a childhood cancer originating from immature nerve
cells in the sympathetic nervous system. Current clinical and molecular subtyping methods …

In neuroblastoma, MYCN amplification and 11q-deletion are important, although incomplete,
markers of high-risk disease. It is therefore relevant to characterize additional alterations that …

Dong et al.(2020) built an atlas of developing neural crest cells and their derivatives in
humans and used it to trace the origins of neuroblastoma. We compared these datasets with …

Objective To investigate the clinicopathological characteristics and long-term survival
outcomes of pediatric adrenal malignancies. Method This study retrospectively analyzed …

Simple Summary Rhabdomyosarcoma is the most common soft tissue cancer in children
and adolescents. Its resemblance to skeletal muscle tissue distinguishes …