Neuroblastoma (NB) is the most common malignant extra cranial solid tumors in children. It
has been well established that retinoic acid (RA) inhibits proliferation of neuroblastoma (NB) …

The mechanism behind the higher incidence of aldosterone-producing adenoma (APA) in
women compared to men is not yet understood. In this study, we utilized single-cell RNA …

Early childhood tumours arise from transformed embryonic cells, which often carry large
copy number alterations (CNA). However, it remains unclear how CNAs contribute to …

Adrenal insufficiency is a life-threatening condition resulting from the inability to produce
adrenal hormones in a dose-and time-dependent manner. Establishing a cell-based therapy …

The use of three-dimensional (3D) bioprinting has remained at the forefront of tissue
engineering and has recently been employed for generating bioprinted solid tumors to be …

Simple Summary In children with metastatic neuroblastoma (NB) the overall survival is still
poor despite aggressive multimodal therapies. Relapse and progression, which are the …

Simple Summary Systems biology analysis of gene expression across solid tumors identifies
a 27 signature that centers on EZH2, the key component of polycomb repressive complex 2 …

Introduction Accumulating evidence demonstrates that aberrant methylation of enhancers is
crucial in gene expression profiles across several cancers. However, the latent effect of …

Neuroblastoma is a pediatric cancer that can present as low-or high-risk tumors (LR-NBs
and HR-NBs), the latter group showing poor prognosis due to metastasis and strong …

Neuroblastoma is the most common extracranial solid tumor of childhood and accounts for a
significant share of childhood cancer deaths. Prior studies utilizing RNA sequencing of bulk …