[HTML][HTML] Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD

M Aghapour, ND Ubags, D Bruder… - European …, 2022 - Eur Respiratory Soc
Chronic exposure to environmental pollutants is a major contributor to the development and
progression of obstructive airway diseases, including asthma and COPD. Understanding the …

Effects of air pollution on human health–mechanistic evidence suggested by in vitro and in vivo modelling

H Chen, BG Oliver, A Pant, A Olivera, P Poronnik… - Environmental …, 2022 - Elsevier
Airborne particulate matter (PM) comprises both solid and liquid particles, including carbon,
sulphates, nitrate, and toxic heavy metals, which can induce oxidative stress and …

Lung adenocarcinoma promotion by air pollutants

W Hill, EL Lim, CE Weeden, C Lee, M Augustine… - Nature, 2023 - nature.com
A complete understanding of how exposure to environmental substances promotes cancer
formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two …

Particulate matter in COPD pathogenesis: an overview

M Kaur, J Chandel, J Malik, AS Naura - Inflammation Research, 2022 - Springer
Chronic obstructive pulmonary disease (COPD) is a progressive lung disorder with
substantial patient burden and leading cause of death globally. Cigarette smoke remains to …

Impact of air pollution on intestinal redox lipidome and microbiome

J Feng, S Cavallero, T Hsiai, R Li - Free Radical Biology and Medicine, 2020 - Elsevier
Air pollution is a rising public health issue worldwide. Cumulative epidemiological and
experimental studies have shown that exposure to air pollution such as particulate matter …

Is there an association between the level of ambient air pollution and COVID-19?

B Wang, H Chen, YL Chan… - American Journal of …, 2020 - journals.physiology.org
Epidemiological studies suggest that environmental factors (eg, air pollution) can influence
the spread and infectivity of coronavirus disease 2019 (COVID-19); however, very few …

Particulate matter impairs immune system function by up-regulating inflammatory pathways and decreasing pathogen response gene expression

D Marín-Palma, GJ Fernandez, J Ruiz-Saenz… - Scientific Reports, 2023 - nature.com
Airborne particulate matter produced by industrial sources and automobiles has been linked
to increased susceptibility to infectious diseases and it is known to be recognized by cells of …

Exposure to urban nanoparticles at low PM concentrations as a source of oxidative stress and inflammation

F Costabile, M Gualtieri, M Rinaldi, S Canepari… - Scientific Reports, 2023 - nature.com
Exposures to fine particulate matter (PM 1) have been associated with health impacts, but
the understanding of the PM 1 concentration-response (PM 1-CR) relationships, especially …

Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories

RE Hynds, KK Frese, DR Pearce… - Open …, 2021 - royalsocietypublishing.org
Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related deaths
worldwide. Although advances are being made towards earlier detection and the …

Role of macrophages in air pollution exposure related asthma

CH Li, ML Tsai, HY Chiou, YC Lin, WT Liao… - International journal of …, 2022 - mdpi.com
Asthma is a chronic inflammatory airway disease characterized by variable airflow
obstruction, bronchial hyper-responsiveness, and airway inflammation. The chronic …