Semaphorins and their receptors, plexins, have emerged as key regulators of various
aspects of neuronal development. In contrast to the Plexin‐A family, the cellular functions of …

Semaphorins and their receptors, plexins, are emerging as key regulators of various aspects
of neural and nonneural development. Semaphorin 4D (Sema4D) and B-type plexins …

Background Semaphorin 4D (Sema4D) is highly expressed in certain types of tumors and
functions in the regulation of tumor angiogenesis and growth. However, it is still not clear …

Abstract Neuroimmune semaphorin 4D (Sema4D) was found to be expressed and function
in the nervous and immune systems. In the immune system, Sema4D is constitutively …

Background The semaphorins and their receptors, the plexins, are proteins related to c-Met
and the scatter factors that have been implicated in an expanding signal transduction …

Platelet activation in vivo can be part of the hemostatic response to injury or a pathological
response to disease. In either setting, platelets adhere to the vessel wall and to each other …

Plexins are transmembrane protein receptors for semaphorin molecules. These molecules
are involved in numerous cellular activities related to cell proliferation, adhesion along with …

Mutations of NKX2-5 largely contribute to congenital heart diseases (CHDs), especially atrial
septal defect (ASD). We identified a novel heterozygous splicing mutation c. 335-1G> A in …

Obesity is a worldwide health problem. Semaphorins are involved in axonal guidance;
however, the role of secretory semaphorin 3G (SEMA3G) in regulating adipocyte …

Plexins serve as receptors for semaphorins and play important roles in the developing
nervous system. Plexin-B2 controls decisive developmental programs in the neural tube and …