A survey of current trends in computational drug repositioning
Computational drug repositioning or repurposing is a promising and efficient tool for
discovering new uses from existing drugs and holds the great potential for precision …
discovering new uses from existing drugs and holds the great potential for precision …
[HTML][HTML] A review of computational drug repurposing
K Park - Translational and clinical pharmacology, 2019 - ncbi.nlm.nih.gov
Although sciences and technology have progressed rapidly, de novo drug development has
been a costly and time-consuming process over the past decades. In view of these …
been a costly and time-consuming process over the past decades. In view of these …
A review of network-based approaches to drug repositioning
M Lotfi Shahreza, N Ghadiri, SR Mousavi… - Briefings in …, 2018 - academic.oup.com
Experimental drug development is time-consuming, expensive and limited to a relatively
small number of targets. However, recent studies show that repositioning of existing drugs …
small number of targets. However, recent studies show that repositioning of existing drugs …
[HTML][HTML] Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer
P Nowak-Sliwinska, L Scapozza, AR i Altaba - Biochimica et Biophysica …, 2019 - Elsevier
The strategy of using existing drugs originally developed for one disease to treat other
indications has found success across medical fields. Such drug repurposing promises faster …
indications has found success across medical fields. Such drug repurposing promises faster …
A bibliometric review of drug repurposing
Highlights•A bibliometric review of drug repurposing provides novel insights into the
practice.•Some drugs have been tried in hundreds of diseases.•Even an old drug like …
practice.•Some drugs have been tried in hundreds of diseases.•Even an old drug like …
Broad-coverage biomedical relation extraction with SemRep
Background In the era of information overload, natural language processing (NLP)
techniques are increasingly needed to support advanced biomedical information …
techniques are increasingly needed to support advanced biomedical information …
Machine learning applications in drug development
Due to the huge amount of biological and medical data available today, along with well-
established machine learning algorithms, the design of largely automated drug development …
established machine learning algorithms, the design of largely automated drug development …
Drug repositioning: new approaches and future prospects for life-debilitating diseases and the COVID-19 pandemic outbreak
Traditionally, drug discovery utilises a de novo design approach, which requires high cost
and many years of drug development before it reaches the market. Novel drug development …
and many years of drug development before it reaches the market. Novel drug development …
Recent advances in biomedical literature mining
The recent years have witnessed a rapid increase in the number of scientific articles in
biomedical domain. These literature are mostly available and readily accessible in …
biomedical domain. These literature are mostly available and readily accessible in …
Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality
Objectives Drug repurposing, which finds new indications for existing drugs, has received
great attention recently. The goal of our work is to assess the feasibility of using electronic …
great attention recently. The goal of our work is to assess the feasibility of using electronic …