Studies of steroid modifications catalyzed by microbial whole cells represent a well-
established research area in white biotechnology. Still, advances over the last decade in …

During the recent 30 years, there has been a dramatic increase in knowledge about the role
of aldosterone and the mineralocorticoid receptor (MR) in the pathophysiology of …

Purpose The principal objective of this trial was to evaluate the antitumor activity of
abiraterone acetate, an oral, specific, irreversible inhibitor of CYP17 in docetaxel-treated …

Cytochrome P450s (CYPs) represent a large class of heme-containing enzymes that
catalyze the metabolism of multitudes of substrates both endogenous and exogenous. Until …

Cytochrome P450s form a large and diverse family of heme-containing proteins capable of
carrying out many different enzymatic reactions. In both mammals and plants, some P450s …

Covering: up to the end of 2006The catalytic potential of the P450s in organic
biotransformations is the subject of this review—with emphasis on the breadth of P450 redox …

It is well known that vitamin C could protect against influenza infection, but little is known
about the mechanisms. This study aimed to investigate the influence and possible …

We previously reported that our novel compound 3β-hydroxy-17-(1 H-benzimidazole-1-yl)
androsta-5, 16-diene (VN/124-1) is a potent 17α-hydroxylase/17, 20-lyase (CYP17) …

Cytochrome P450s play critical roles in the metabolism of various bioactive compounds.
One of the crucial functions of cytochrome P450s in Chordata is in the biosynthesis of steroid …

Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TCPP), a prevalent organophosphorus
flame retardant in aquatic environments, has raised significant concerns regarding its …