Systems toxicology approach explores target-pathway relationship and adverse health impacts of ubiquitous environmental pollutant bisphenol A
M Nagarajan, GB Maadurshni… - Journal of Toxicology …, 2022 - Taylor & Francis
The effects of environmental chemicals on health outcomes may be underestimated due to
deficiency of knowledge regarding the actions of compounds on toxico-pathogenic …
deficiency of knowledge regarding the actions of compounds on toxico-pathogenic …
System-wide health risk prediction for 4-methyl-2, 4-bis (4-hydroxyphenyl) pent-1-ene (MBP), a major active metabolite of environmental pollutant and food …
GB Maadurshni, M Nagarajan, S Priyadharshini… - Toxicology, 2023 - Elsevier
Human exposure to plastic contaminated foods and environmental micro/nano plastic
derived chemicals necessitates system-wide health risk assessment. Hence, current study …
derived chemicals necessitates system-wide health risk assessment. Hence, current study …
[图书][B] Modelling of quantitative Adverse Outcome Pathways
N Spînu - 2021 - search.proquest.com
With the growth of green chemistry initiatives, there is a demand for improved regulatory
assessment of human exposure to exogenous factors. Proposed a decade ago, the adverse …
assessment of human exposure to exogenous factors. Proposed a decade ago, the adverse …
Transcriptional analyses of acute per os exposure and co-exposure of 4-vinylcyclohexene and methylmercury-contaminated diet in adults of Drosophila melanogaster
Continuous exposure to low levels of toxic substances can be associated with delayed
physical disturbances, which can be preceded by changes in enzyme activities and gene …
physical disturbances, which can be preceded by changes in enzyme activities and gene …
Shotgun Lipidomics of Rodent Tissues
O Lavrynenko, S Dijon, B Titz, NV Ivanov - JoVE (Journal of Visualized …, 2022 - jove.com
Lipids play a vital role as essential components of all prokaryotic and eukaryotic cells.
Constant technological improvements in mass spectrometry have made lipidomics a …
Constant technological improvements in mass spectrometry have made lipidomics a …
Effect of Endosulfan Organochlorine-based Insecticide on Human Mental Health at the Molecular Level using Panther
D Sharma, T Shiri, A Kapri, V Sharma - Analytical Chemistry …, 2021 - Taylor & Francis
Endosulfan is an organochlorine insecticide that is extensively used in agriculture. Humans
get exposed to this contaminant either directly through farms or indirectly by consumption of …
get exposed to this contaminant either directly through farms or indirectly by consumption of …
Prospects and limitations of physiologically-based pharmacokinetic modelling for cross-species extrapolation
L Kuepfer - SVU-International Journal of Veterinary Sciences, 2019 - journals.ekb.eg
The transition from experimental findings in animal models to clinical applications in human
patients is a key challenge in pharmacology and toxicology. To date, this steps still inhibits a …
patients is a key challenge in pharmacology and toxicology. To date, this steps still inhibits a …
[HTML][HTML] Sub-lethal effects of calcium dinonylnaphthalenesulfonate on Western clawed frog embryos
SJ Wallace, AJA Leclerc, R Prosser… - … and Physiology Part D …, 2020 - Elsevier
Naphthalene sulfonic acids (NSAs) are used as additives in lubricants, dyes, and greases
and commonly act as surfactants in many industrial processes. The calcium salt of dinonyl …
and commonly act as surfactants in many industrial processes. The calcium salt of dinonyl …
Drug development
FI Raynaud - Metabolomics for Biomedical Research, 2020 - Elsevier
Successful drug discovery relies on understanding disease causality and identifying a
druggable target for therapeutic intervention. Metabolomics is a welcome complement to …
druggable target for therapeutic intervention. Metabolomics is a welcome complement to …
Toxicopanomics: Application of Genomics, Transcriptomics, Proteomics, Metabolomics, and Lipidomics in Predictive Mechanistic Toxicology
MA Choukrallah, M Talikka, S Boue… - … and Methods of …, 2023 - books.google.com
Systems toxicology is a subdiscipline of systems biology that aims to provide a holistic view
of biological processes by using systems-wide molecular measurements, which are …
of biological processes by using systems-wide molecular measurements, which are …