Serotonin (5-hydroxytryptamine; 5-HT) is a monoamine neurotransmitter whose effects are
mediated by at least 13 distinct G protein-coupled receptors (GPCRs) of the type A family …

Background The nonselective 5‐HT 4 receptor agonists, cisapride and tegaserod have been
associated with cardiovascular adverse events (AEs). Aim To perform a systematic review of …

G protein-coupled receptors (GPCRs) are involved in numerous key neurotransmitter
systems in the brain that are disrupted in Alzheimer's disease (AD). GPCRs also directly …

The human cardiovascular system is exposed to plasma 5-hydroxytryptamine (5-HT,
serotonin), usually released from platelets. 5-HT can produce harmful acute and chronic …

Serotonin 4 receptors (5-HT4Rs) were discovered 15 years ago. They are codedby a very
complex gene (700Kb, 38 exons) which generates eight carboxy-terminalvariants (a, b, c, d …

We evaluated whether a probiotic supplementation in dogs with food responsive diarrhoea
(FRD) has beneficial effects on intestinal cytokine patterns and on microbiota. Twenty‐one …

Abstract Serotonin (5-hydroxytryptamine or 5-HT) plays a critical physiological role in the
regulation of gastrointestinal (GI) function. 5-HT dysfunction may also be involved in the …

The 5-hydroxytryptamine type 4 receptor (5-HT4R) is involved in learning, feeding,
respiratory control and gastrointestinal transit. This receptor is one of the G-protein-coupled …

The aim of the current study was to identify enteric 5-HT4 splice variants, locate enteric 5-
HT4 receptors, determine the relationship, if any, of the 5-HT4 receptor to 5-HT1P activity …

Acute myocardial infarction (AMI) is one of the leading causes of death worldwide and
treatment costs pose a major burden on the global health care system. Despite the variety of …