[HTML][HTML] Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols

J Moore, M Yousef, E Tsiani - Nutrients, 2016 - mdpi.com
Cancer cells display enhanced growth rates and a resistance to apoptosis. The ability of
cancer cells to evade homeostasis and proliferate uncontrollably while avoiding …

[HTML][HTML] Rosmarinic acid and related dietary supplements: Potential applications in the prevention and treatment of cancer

J Zhao, L Xu, D Jin, Y Xin, L Tian, T Wang, D Zhao… - Biomolecules, 2022 - mdpi.com
Cancer constitutes a severe threat to human health and quality of life and is one of the most
significant causes of morbidity and mortality worldwide. Natural dietary products have drawn …

Antioxidant activity of rosmarinic acid and its principal metabolites in chemical and cellular systems: Importance of physico-chemical characteristics

AG Adomako-Bonsu, SLF Chan, M Pratten, JR Fry - Toxicology in vitro, 2017 - Elsevier
Persistent accumulation of reactive oxygen species causes cellular oxidative stress which
contributes strongly towards the induction and progression of various diseases. Therapeutic …

[HTML][HTML] Exploring the potential of rosemary derived compounds (rosmarinic and carnosic acids) as cancer therapeutics: current knowledge and future perspectives

F Sirajudeen, LJB Malhab, Y Bustanji… - Biomolecules & …, 2024 - ncbi.nlm.nih.gov
Cancer is a global health challenge with high morbidity and mortality rates. However,
conventional cancer treatment methods often have severe side effects and limited success …

Licochalcone A, a licorice flavonoid: Antioxidant, cytotoxic, genotoxic, and chemopreventive potential

KS de Freitas, IS Squarisi, NO Acesio… - Journal of Toxicology …, 2020 - Taylor & Francis
Licochalcone A (LicoA) is a flavonoid derived from Glycyrrhiza spp. plants. The present
study aimed to investigate the antioxidant, cytotoxic, genotoxic, and chemopreventive effects …

[HTML][HTML] Therapeutic benefits of Salvia species: A focus on cancer and viral infection

CA Ezema, TPC Ezeorba, RN Aguchem, IU Okagu - Heliyon, 2022 - cell.com
Man is increasingly being faced with many health conditions, including viral infection, some
of which increases the risk to cancer. These infectious agents contribute to the large number …

Biochemical and molecular mechanisms underlying the chemopreventive efficacy of rosmarinic acid in a rat colon cancer

K Venkatachalam, S Gunasekaran… - European Journal of …, 2016 - Elsevier
To shed light on colon cancer chemoprevention, natural phytochemicals attract researchers
by virtue of their beneficial biological effects. The chemopreventive potential of rosmarinic …

Nephroprotective effect of green tea, rosmarinic acid and rosemary on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute renal toxicity in Wistar …

MA El-Desouky, MH Mahmoud, BY Riad… - Interdisciplinary …, 2019 - sciendo.com
The present study was designed to investigate the chemoprotective effect of green tea
extract (GTE), rosmarinic acid (RA) and rosemary extract (RE) against diethylnitrosamine …

Novel 1, 3, 4-thiadiazoles inhibit colorectal cancer via blockade of IL-6/COX-2 mediated JAK2/STAT3 signals as evidenced through data-based mathematical …

V Raj, AS Bhadauria, AK Singh, U Kumar, A Rai… - Cytokine, 2019 - Elsevier
We attempted a preclinical study using DMH-induced CRC rat model to evaluate the
antitumor potential of our recently synthesized 1, 3, 4-thiadiazoles. The molecular insights …

Potent antitumor activity of Laccaic acid and Phenethyl isothiocyanate combination in colorectal cancer via dual inhibition of DNA methyltransferase-1 and Histone …

R Gupta, LK Bhatt, M Momin - Toxicology and Applied Pharmacology, 2019 - Elsevier
Despite an incessant advancement in the treatment of Colorectal Cancer (CRC), 40% of
individuals suffer from disease relapse which marks the need for new treatment options. In …