[HTML][HTML] Continuous manufacturing of solvent-free cyclodextrin inclusion complexes for enhanced drug solubility via hot-melt extrusion: a quality by design approach

SR Munnangi, AAA Youssef, N Narala, P Lakkala… - Pharmaceutics, 2023 - mdpi.com
Conventional cyclodextrin complexation enhances the solubility of poorly soluble drugs but
is solvent-intensive and environmentally unfavorable. This study evaluated solvent-free hot …

The role of artificial intelligence and data science in nanoparticles development: a review

RF Silveira, AL Lima, IP Gross, GM Gelfuso… - …, 2024 - Taylor & Francis
Artificial intelligence has revolutionized many sectors with unparalleled predictive
capabilities supported by machine learning (ML). So far, this tool has not been able to …

Quality by design approach for fabrication of extended-release buccal films for xerostomia employing hot-melt extrusion technology

RM Elkanayati, AY Darwesh, I Taha, H Wang… - European Journal of …, 2024 - Elsevier
The study endeavors the fabrication of extended-release adipic acid (APA) buccal films
employing a quality by design (QbD) approach. The films intended for the treatment of …

[HTML][HTML] Agile quality-by-design development of alginate microparticles for encapsulation of hydrophilic drug

ARS Mackin-Mohamour, J Budzinski… - Colloids and Surfaces A …, 2024 - Elsevier
The development of alginate microparticles for encapsulation of hydrophilic drug is
addressed. The alginate microparticles are produced by the emulsification/gelation process …

[PDF][PDF] Continuous Manufacturing of Solvent-Free Cyclodextrin Inclusion Complexes for Enhanced Drug Solubility via Hot-Melt Extrusion: A Quality by Design …

SR Munnangi, AAA Youssef, N Narala, P Lakkala… - 2023 - academia.edu
Conventional cyclodextrin complexation enhances the solubility of poorly soluble drugs but
is solvent-intensive and environmentally unfavorable. This study evaluated solvent-free …

[PDF][PDF] Research News, Publications, 2021, Volume 3

S Majumdar - 2021 - egrove.olemiss.edu
22. De La Cruz LK, Yang X, Menshikh A, Brewer M, Lu W, Wang M, Wang S, Ji X, Cachuela
A, Yang H, Gallo D, Tan C, Otterbein L, de Caestecker M, Wang B. Adapting decarbonylation …