Review of recent developments in GC–MS approaches to metabolomics-based research

DJ Beale, FR Pinu, KA Kouremenos, MM Poojary… - Metabolomics, 2018 - Springer
Background Metabolomics aims to identify the changes in endogenous metabolites of
biological systems in response to intrinsic and extrinsic factors. This is accomplished …

[HTML][HTML] The chemistry of plant–microbe interactions in the rhizosphere and the potential for metabolomics to reveal signaling related to defense priming and induced …

MI Mhlongo, LA Piater, NE Madala… - Frontiers in plant …, 2018 - frontiersin.org
Plant roots communicate with microbes in a sophisticated manner through chemical
communication within the rhizosphere, thereby leading to biofilm formation of beneficial …

A tutorial review: Metabolomics and partial least squares-discriminant analysis–a marriage of convenience or a shotgun wedding

PS Gromski, H Muhamadali, DI Ellis, Y Xu, E Correa… - Analytica chimica …, 2015 - Elsevier
The predominance of partial least squares-discriminant analysis (PLS-DA) used to analyze
metabolomics datasets (indeed, it is the most well-known tool to perform classification and …

Quantitative mass spectrometry imaging of biological systems

D Unsihuay, D Mesa Sanchez… - Annual review of physical …, 2021 - annualreviews.org
Mass spectrometry imaging (MSI) is a powerful, label-free technique that provides detailed
maps of hundreds of molecules in complex samples with high sensitivity and subcellular …

[HTML][HTML] Extraction of high-value chemicals from plants for technical and medical applications

P Kapadia, AS Newell, J Cunningham… - International journal of …, 2022 - mdpi.com
Plants produce a variety of high-value chemicals (eg, secondary metabolites) which have a
plethora of biological activities, which may be utilised in many facets of industry (eg …

Current approaches and challenges for the metabolite profiling of complex natural extracts

JL Wolfender, G Marti, A Thomas, S Bertrand - Journal of Chromatography …, 2015 - Elsevier
Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

[HTML][HTML] Metabolomics for plant improvement: status and prospects

R Kumar, A Bohra, AK Pandey, MK Pandey… - Frontiers in Plant …, 2017 - frontiersin.org
Post-genomics era has witnessed the development of cutting-edge technologies that have
offered cost-efficient and high-throughput ways for molecular characterization of the function …

[HTML][HTML] The use of metabolomics to dissect plant responses to abiotic stresses

T Obata, AR Fernie - Cellular and Molecular Life Sciences, 2012 - Springer
Plant metabolism is perturbed by various abiotic stresses. As such the metabolic network of
plants must be reconfigured under stress conditions in order to allow both the maintenance …

[HTML][HTML] How close are we to complete annotation of metabolomes?

MR Viant, IJ Kurland, MR Jones, WB Dunn - Current opinion in chemical …, 2017 - Elsevier
Highlights•No exhaustive experimental characterisation of an organism's metabolome
reported.•Deep metabolome annotation strategies based on multi-platform …