Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Background Doxorubicin (DOX) is a powerful anti-tumor anthracycline drug. However, its
clinical use is limited due to the side effect of cardiotoxicity. Tanshinone I (Tan I) is one of the …

Background Ginseng is well-known as one of the most valuable and commonly used
Chinese medicines not only in ancient China but also worldwide including East, Russia …

The goal of this study was to analyze whether mitochondria-associated endoplasmic
reticulum membrane (MAMs) dysfunction mediated arsenic (As)-evoked pulmonary …

Ethnopharmacological relevance Doxorubicin (DOX) is one of the most potent
chemotherapy drugs available today. However, the adverse effect of cardiotoxicity limits its …

Cardiotoxicity linked to doxorubicin (DOX) is primarily caused by inflammation, oxidative
stress, and apoptosis. The role of tubeimoside I (TBM) in DOX‐induced cardiotoxicity …

Herein, a doxorubicin-loaded carbon-based drug delivery system, denoted as PC-DOX,
composed of pH-responsive imine bond was developed for the tumor-targeted treatment. PC …

Clinical application of doxorubicin (Dox) in cancer chemotherapy is limited by its
cardiotoxicity. Present study aimed to demonstrate the effect and mechanism of hyperoside …

To investigate anti-inflammatory effects and molecular mechanisms of polysaccharides
derived from Apocynum venetum L. roots on lipopolysaccharide (LPS)-induced mouse …

Although chemotherapy drugs are extensively utilized in cancer therapy, their administration
for treatment of patients has faced problems that regardless of chemoresistance, increasing …